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C1510000

Chlorhexidine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

1,1′-Hexamethylenebis[5-(4-chlorophenyl)biguanide]

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About This Item

Fórmula lineal:
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
Número de CAS:
55-56-1
Peso molecular:
505.45
Beilstein:
2826432
Número MDL:
MFCD00009673
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329774893
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

chlorhexidine

fabricante / nombre comercial

EDQM

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

134-136 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

Clave InChI

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Chlorhexidine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

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Pictogramas

CorrosionEnvironment
GHS05,GHS09

Palabra de señalización

Danger

Frases de peligro

H318,H410

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Carolyne Horner et al.
The Journal of antimicrobial chemotherapy, 67(11), 2547-2559 (2012-07-27)
Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical
Lennie P G Derde et al.
The Lancet. Infectious diseases, 14(1), 31-39 (2013-10-29)
Intensive care units (ICUs) are high-risk areas for transmission of antimicrobial-resistant bacteria, but no controlled study has tested the effect of rapid screening and isolation of carriers on transmission in settings with best-standard precautions. We assessed interventions to reduce colonisation
Afshin Haraji et al.
Journal of orofacial pain, 27(3), 256-262 (2013-07-25)
To assess the effects of intra-alveolar application of chlorhexidine gel on the incidence of alveolar osteitis (dry socket) and the severity of postsurgical pain. A total of 160 impacted mandibular third molars were extracted in 80 patients enrolled in this
Dana Robaei et al.
Ophthalmology, 121(7), 1383-1388 (2014-03-19)
To examine the impact of topical corticosteroid use before the diagnosis of Acanthamoeba keratitis (AK) on final visual outcomes and to determine the prognostic factors predicting poorer outcomes. Cohort study. A total of 209 eyes of 196 patients with retrievable
Richard Price et al.
BMJ (Clinical research ed.), 348, g2197-g2197 (2014-04-02)
To determine the effect on mortality of selective digestive decontamination, selective oropharyngeal decontamination, and topical oropharyngeal chlorhexidine in adult patients in general intensive care units and to compare these interventions with each other in a network meta-analysis. Systematic review, conventional
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