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BCR309

6-Nitrochrysene

BCR®, certified reference material

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About This Item

Fórmula empírica (notación de Hill):
C18H11NO2
Número de CAS:
7496-02-8
Peso molecular:
273.29
Beilstein/REAXYS Number:
2134652
MDL number:
MFCD00021179
UNSPSC Code:
41116107
PubChem Substance ID:
329773818
NACRES:
NA.24

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

220 °C (dec.) (lit.)

format

neat

storage temp.

2-8°C

SMILES string

[O-][N+](=O)c1cc2c3ccccc3ccc2c4ccccc14

InChI

1S/C18H11NO2/c20-19(21)18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H

InChI key

UAWLTQJFZUYROA-UHFFFAOYSA-N

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Application

6-Nitrochrysene may be used as a certified reference material for the quantification of the analyte in air samples, standard reference material 1649a (urban dust), air and diesel particulate reference materials using gas chromatography-mass spectrometry with negative ion chemical ionization (GC/NICI-MS).

Analysis Note

For more information please see:
BCR309

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Sigma-Aldrich

F1506

9-Fluorenone

Karam El-Bayoumy et al.
Chemical research in toxicology, 15(7), 972-978 (2002-07-18)
Human exposure to the class of nitropolynuclear aromatic hydrocarbons is via inhalation and/or ingestion. Therefore, one of the goals of this study was to determine the propensity of the environmental contaminant 6-nitrochrysene (6-NC) for inducing mammary cancer following its oral
J Krzeminski et al.
Chemical research in toxicology, 13(11), 1143-1148 (2000-11-23)
The remarkable carcinogenic activity of 6-nitrochrysene (6-NC) in several animal models, and its environmental presence, suggest its potential importance with regard to human cancer development. Depending on the bioassay model, 6-NC can be activated by simple nitro reduction, ring oxidation
Y H Chae et al.
Cancer research, 56(9), 2052-2058 (1996-05-01)
The environmental contaminant 6-nitrochrysene (6-NC) has been shown to induce adenomas and adenocarcinomas in the colons of rats. The present study aimed at providing a better understanding of mechanisms that are responsible for this effect. Three female CD rats were
C R Valentine et al.
Environmental and molecular mutagenesis, 25(2), 85-96 (1995-01-01)
We have analyzed 41 mRNA-splicing mutants from the hypoxanthine-guanine phosphoribosyl-transferase (hprt) gene of Chinese hamster ovary (CHO) cells. Twenty-two of these mutants produced single cDNA PCR products with a partial or complete exon deletion; 19 mutants produced multiple cDNA PCR
R M Chen et al.
Archives of toxicology, 72(7), 395-401 (1998-08-26)
The present study has determined the effect of 6-nitrochrysene (6-NC) on hepatic and pulmonary cytochrome P450 (P450)-dependent monooxygenases using hamsters pretreated with the nitrated polycyclic aromatic hydrocarbon (nitro-PAH) at 5 mg/kg per day for 3 days. Pretreatment with 6-NC elevated
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