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Key Documents

B0490000

Benzarone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone, NSC 82134

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About This Item

Fórmula empírica (notación de Hill):
C17H14O3
Número de CAS:
1477-19-6
Peso molecular:
266.29
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

benzarone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)10-8-11/h3-10,18H,2H2,1H3

InChI key

RFRXIWQYSOIBDI-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benzarone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Certificados de análisis (COA)

Lot/Batch Number

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Benzaron allergy.
I Pevny
Contact dermatitis, 11(2), 122-122 (1984-08-01)
I Walter-Sack et al.
Klinische Wochenschrift, 66(4), 160-166 (1988-02-15)
Benzbromarone is one of the main uricosuric drugs currently used. We determined plasma concentrations of benzbromarone, bromobenzarone, and benzarone and 24 hour uric acid excretion in ten healthy individuals following fasting application of two different non-micronised benzbromarone brands. In addition
H Köstering et al.
Arzneimittel-Forschung, 35(8), 1303-1306 (1985-01-01)
The analyses on hemostaseological variables are recorded in connection with blood tests in the course of a double-blind study in 41 patients suffering from chronic venous insufficiency of higher degrees of severity. They were treated in addition to compression measures
H E Knehr et al.
Arzneimittel-Forschung, 33(2), 211-214 (1983-01-01)
The influence of 2-ethyl-3-(4-hydroxy-benzoyl)-benzofurane (benzarone, Fragivic) on the energy metabolism of the wall of the rabbit common carotid artery and the rat portal vein was investigated by measuring the oxygen consumption of in vitro incubated vessel segments. Benzarone increased the
Priska Kaufmann et al.
Hepatology (Baltimore, Md.), 41(4), 925-935 (2005-03-31)
Treatment with benzarone or benzbromarone can be associated with hepatic injury. Both drugs share structural similarities with amiodarone, a well-known mitochondrial toxin. Therefore, we investigated the hepatotoxicity of benzarone and benzbromarone as well as the analogues benzofuran and 2-butylbenzofuran. In
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