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Merck

A9199

Sigma-Aldrich

2-amino-2-metil-1-propanol

BioXtra, ≥95%

Sinónimos:

βAlcohol β-aminoisobutílico, AMP

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About This Item

Fórmula lineal:
(CH3)2C(NH2)CH2OH
Número de CAS:
Peso molecular:
89.14
Beilstein/REAXYS Number:
505979
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

vapor density

3 (vs air)

Quality Level

vapor pressure

<1 mmHg ( 25 °C)

product line

BioXtra

assay

≥95%

form

liquid

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

refractive index

n20/D 1.4455 (lit.)

pH

11.0-12 (25 °C, 8.9 g/L)

useful pH range

9.0-10.5

pKa (25 °C)

9.7

bp

165 °C (lit.)

mp

24-28 °C (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

density

0.934 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

CC(C)(N)CO

InChI

1S/C4H11NO/c1-4(2,5)3-6/h6H,3,5H2,1-2H3

InChI key

CBTVGIZVANVGBH-UHFFFAOYSA-N

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Application

2-Amino-2-methyl-1-propanol has been used as an component in enzyme assay for screening the alkaline phosphatase activity in sarcoma osteogenic (SaOS-2) cells..

Biochem/physiol Actions

2-Amino-2-methyl-1-propanol is a substituted aliphatic alcohol and is used majorly as a pH balancer in cosmetic formulations. It has phototoxic effect as it can interact and penetrate above the sebum layer. However, it is not carcinogenic.

pictograms

Corrosion

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

179.8 °F - closed cup

flash_point_c

82.1 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol
Burnett CL, et al.
International Journal of Toxicology, 28(6), 141S-161S (2009)
Phototoxic assessment of a sunscreen formulation and its excipients: An in vivo and in vitro study
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R A Stinson
Clinical chemistry, 39(11 Pt 1), 2293-2297 (1993-11-01)
Nine different isoenzymes and (or) isoforms of alkaline phosphatase (ALP; EC 3.1.3.1) from human tissue were studied with respect to Km and Vmax values for p-nitrophenyl phosphate (p-NPP) in seven different potential phosphoacceptors/buffers. Generally, the phosphoacceptors/buffers with the lowest affinity
Won-Joon Choi et al.
Journal of environmental sciences (China), 21(7), 907-913 (2009-10-30)
The carbon dioxide (CO2) removal efficiency, reaction rate, and CO2 loading into aqueous blended monoethanolamine (MEA) + 2-amino-2-methyl-1-propanol (AMP) solutions to enhance absorption characteristics of MEA and AMP were carried out by the absorption/regeneration process. As a result, compared to

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