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Merck

94972

Supelco

Brombuterol hydrochloride

VETRANAL®, analytical standard

Sinónimos:

1-(4-Amino-3,5-dibromophenyl)-2-tert-butylaminoethanol hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C12H18Br2N2O · HCl
Número de CAS:
Peso molecular:
402.55
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.CC(C)(C)NCC(O)c1cc(Br)c(N)c(Br)c1

InChI

1S/C12H18Br2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

InChI key

XGPFKIAOVSGRSY-UHFFFAOYSA-N

General description

Brombuterol hydrochloride is a beta-sympathomimetic compound with tocolytic, muscle-relaxant and bronchodilator properties and is widely used in therapy for their growth promoting and performance enhancement.

Application

Brombuterol hydrochloride may be used as an analytical reference standard for the quantification of the analyte in complex matrices and biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Visite la Librería de documentos

E Sangiorgi et al.
Journal of chromatography. B, Biomedical sciences and applications, 693(2), 468-478 (1997-06-06)
The multistep analytical procedure routinely applied in our laboratory for the detection of the aryl amine beta-agonists clenbuterol, mabuterol and mapenterol in bovine matrices has been extended to the analysis in urine samples of brombuterol, a new clenbuterol-like compound. In
C Montesissa et al.
Xenobiotica; the fate of foreign compounds in biological systems, 28(11), 1049-1060 (1999-01-08)
1. Clenbuterol (CBL) and bromobuterol (BBL) were both extensively metabolized by hepatic microsomes of swine to only one polar metabolite which was separated by hplc and purified to perform mass analysis. 2. LC-MIS analysis by direct infusion into an ion
Overcoming matrix effects in electrospray: Quantitation of ?-agonists in complex matrices by isotope dilution liquid chromatography?mass spectrometry using singly 13C-labeled analogues
Gonzalez-Antuna A, et al.
Journal of Chromatography A, 40-47 (2013)
Analysis of beta-agonist residues in bovine hair: Development of a UPLC?MS/MS method and stability study
Giannetti L, et al.
Journal of Chromatography. B, Biomedical Applications, 1036(3), 76-83 (2016)
Leslie C Dickson et al.
Journal of AOAC International, 88(1), 46-56 (2005-03-12)
A multiresidue method was developed and validated to screen bovine urine samples for 10 beta-2-adrenergic agonistic drugs--brombuterol, cimaterol, clenbuterol, clenpenterol, isoxsuprine, mabuterol, ractopamine, ritodrine, salbutamol, and tulobuterol--at the 2 microg/L level. The method is also quantitative in the range of

Artículos

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

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