93813

Cyclophosphamide monohydrate

analytical standard

• Sinónimos: 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• Fórmula empírica (notación de Hill): C₇H₁₅Cl₂N₂O₂P · H₂O
• Número de CAS: 6055-19-2
• Peso molecular: 279.10
• Beilstein/REAXYS Number: 4678992
• EC Number: 200-015-4
• MDL number: MFCD00149395
• UNSPSC Code: 41116107
• PubChem Substance ID: 329770272
• NACRES: NA.24

Propiedades

• grade: analytical standard
• Quality Level: 100
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: 6.45% water (theory, monohydrate)
• mp: 47-52 °C; 49-51 °C (lit.)
• application(s): forensics and toxicology; veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChI key: PWOQRKCAHTVFLB-UHFFFAOYSA-N

Descripción

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H340,H350,H360FD
• pcodes: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3