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Merck

91827

Supelco

Biotina

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Sinónimos:

D-Biotina, Bios II, Coenzima R, Vitamina H, Vitaminas B7

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About This Item

Fórmula empírica (notación de Hill):
C10H16N2O3S
Número de CAS:
Peso molecular:
244.31
Beilstein:
86838
Número CE:
Número MDL:
Código UNSPSC:
41116107
eCl@ss:
34058011
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
TraceCERT®

Nivel de calidad

Línea del producto

TraceCERT®

caducidad

limited shelf life, expiry date on the label

fabricante / nombre comercial

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

técnicas

HPLC: suitable
LC/MS: suitable
gas chromatography (GC): suitable

color

white

mp

231-233 °C (lit.)

aplicaciones

clinical testing
pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

Clave InChI

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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Descripción general

Biotin is a bicyclic compound, which is widely distributed in food stuffs. It is essentially required as an important nutrient for animals.
Biotin is a water soluble vitamin, which functions as a coenzyme in several carboxylase-mediated metabolic reactions such as gluconeogenesis, biosynthesis of fatty acids, and metabolism of amino acids.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

Aplicación

Biotin may be used as a certified reference material for the quantification of the analyte in food samples, feed, tablets and premixes using high-performance liquid chromatography/avidin binding and high-performance liquid chromatography with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Información legal

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Nutrient Requirements of Dogs and Cats (2006)
Quantification of biotin in feed, food, tablets, and premixes using HPLC?MS/MS
Holler U, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 831(1-2), 8-16 (2006)
Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding
Staggs GC, et al.
J. Food Compos. Anal., 17(6), 767-776 (2004)
Sung Jae Shin et al.
Clinical and vaccine immunology : CVI, 15(8), 1277-1281 (2008-06-14)
We previously reported that protein antigens of serodiagnostic potential were more abundant in culture filtrates than cellular extracts from liquid cultures of Mycobacterium avium subsp. paratuberculosis (D. Cho and M. T. Collins, Clin. Vaccine Immunol. 13:1155-1161, 2006). Based on this
Yuxi Feng et al.
PloS one, 6(2), e16865-e16865 (2011-03-08)
Vasoregression is a hallmark of vascular eye diseases but the mechanisms involved are still largely unknown. We have recently characterized a rat ciliopathy model which develops primary photoreceptor degeneration and secondary vasoregression. To improve the understanding of secondary vasoregression in

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