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Key Documents

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33656

Supelco

Semicarbazide hydrochloride

VETRANAL®, analytical standard

Sinónimos:

N-Aminourea hydrochloride, Hydrazine carboxamide hydrochloride

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About This Item

Fórmula lineal:
NH2CONHNH2 · HCl
Número de CAS:
563-41-7
Peso molecular:
111.53
Beilstein/REAXYS Number:
3593642
EC Number:
209-247-0
MDL number:
MFCD00013009
UNSPSC Code:
41116107
PubChem Substance ID:
329754605
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

175-177 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl.NNC(N)=O

InChI

1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

InChI key

XHQYBDSXTDXSHY-UHFFFAOYSA-N

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Categorías relacionadas

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Semicarbazide hydrochloride may be used as a stabilizing agent for the determination of norepinephrine in plasma samples using stable-isotope dilution gas chromatography-tandem mass spectrometry with negative ion chemical ionization.
Semicarbazide hydrochloride may be used in the synthesis of 4-nitrobenzaldehyde semicarbazone via reaction with 4-nitrobenzaldehyde.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Oral

target_organs

Bone

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
BCCG5699
BCCG5696
BCBV0190
BCBV0139
SZBD324XV

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Determination of norepinephrine in small volume plasma samples by stable-isotope dilution gas chromatography-tandem mass spectrometry with negative ion chemical ionization.
Kuhlenbeck LD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 738(2), 319-330 (2000)
Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography?tandem mass spectrometry
Leitner A, et al.
Journal of Chromatography A, 939, 49-58 (2001)
Jainendra Jain et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 6(1), 44-50 (2010-04-21)
A series of novel (+/-) 3-menthone semi carbazides (1-7) and thiosemicarbazides synthesized using an appropriate synthetic route and characterized by thin layer chromatography and spectral analysis. The anticonvulsant activity of synthesized compounds was established after intraperitoneal administration in three seizure
N Raman et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 76(2), 161-173 (2010-04-07)
We depict the synthesis and characterization of copper(II) and zinc(II) coordination compounds of 4-(3',4'-dimethoxybenzaldehydene)2-3-dimethyl-1-phenyl-3-pyrazolin-5-semicarbazone (1a), 4-(3',4'-dimethoxybenzaldehydene)2-3-dimethyl-1-phenyl-3-pyrazolin-5-thiosemicarbazone (1b), 4-(3'-hydroxy-4'-nitrobenzaldehydene)2-3-dimeth yl-1-phenyl-3-pyrazolin-5-semicarbazone (1c) and 4-(3'-hydroxy-4'-nitrobenzal dehydene)2-3-dimethyl-1-phenyl-3-pyrazolin-5-thiosemicarbazone (1d). All the remote compounds have the general composition [ML(2)] (M=Cu(II) and Zn(II)); L=Schiff base (1a-1d). All
Haejung An et al.
Journal of AOAC International, 95(4), 1222-1233 (2012-09-14)
The method of MacMahon and Lohne for analysis of nitrofuran metabolites in shrimp was optimized to streamline the extraction processes and the LC analysis. This revised method includes 16 h of mild acid hydrolysis/derivatization followed by ethyl acetate extraction and
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