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Merck

33262

Sigma-Aldrich

1,3-Diamino-2-propanol

purum, ≥96.5% (GC)

Sinónimos:

1,3-Diamino-2-hydroxypropane

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About This Item

Fórmula lineal:
NH2CH2CH(OH)CH2NH2
Número de CAS:
Peso molecular:
90.12
Beilstein/REAXYS Number:
741859
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

purum

Quality Level

assay

≥96.5% (GC)

form

solid

impurities

≤2.0% water

mp

40-44 °C (lit.)

solubility

water: soluble 1 g/10 mL

functional group

amine
hydroxyl

storage temp.

2-8°C

SMILES string

NCC(O)CN

InChI

1S/C3H10N2O/c4-1-3(6)2-5/h3,6H,1-2,4-5H2

InChI key

UYBWIEGTWASWSR-UHFFFAOYSA-N

Gene Information

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Application

1,3-Diamino-2-propanol was used in the synthesis of poly(2-hydroxypropylene imine), poly(2-hydroxypropylene imine ethylene imine) and poly(hydroxypropylene imine propylene imine). It was also used in the synthesis of tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole group.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Sachindranath Pal et al.
Inorganic chemistry, 44(11), 3880-3889 (2005-05-24)
A tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole and copper(II) and nickel(II) complexes of the Schiff base having N-donor atoms have been investigated. A 2 equiv amount of 5-methyl-3-formylpyrazole (MPA) and 2 equiv
L Alhonen-Hongisto
The Biochemical journal, 190(3), 747-754 (1980-09-15)
1. The mechanism of stimulation of S-adenosylmethionine decarboxylase (EC 4.1.1.50) activity by inhibitors of ornithine decarboxylase (EC 4.1.1.17), namely dl-alpha-difluoromethylornithine, 1,3-diaminopropane and 1,3-diaminopropan-2-ol, was studied in Ehrlich ascites-tumour cells grown in suspension cultures. 2. Difluoromethylornithine and diaminopropane, although decreasing the
Y W Hu et al.
Canadian journal of physiology and pharmacology, 60(12), 1493-1498 (1982-12-01)
The effect of diaminopropanol, an inhibitor of polyamine synthesis, on the metabolic response of liver to insulin was studied in streptozotocin-diabetic rats. Insulin elicited a prompt and very marked increase in ornithine and S-adenosylmethionine decarboxylase activities and in putrescine concentration.
M Mach et al.
The Biochemical journal, 202(1), 153-162 (1982-01-15)
Inhibitors of polyamine synthesis (alpha-methylornithine and 1,3-diaminopropan-2-ol) were used to study the relationship between polyamine synthesis and specific methylations of tRNA in Dictyostelium discoideum during vegetative growth. Polyamine concentrations were found to be 10 mM for putrescine, 1.6 mM for
J M Matés et al.
Biochemical pharmacology, 42(5), 1045-1052 (1991-08-08)
Ornithine decarboxylase (ODC) activity of Ehrlich carcinoma cells was increased more than 36-fold after being maintained for 3.5 hr in vitro in a special chamber which allowed continuous perifusion with 0.5 mM ornithine; if incubated in vitro without perifusion the

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