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Merck

125660

Sigma-Aldrich

Leucomalachite Green

powder

Sinónimos:

4,4′-Benzylidenebis(N,N-dimethylaniline)

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About This Item

Fórmula lineal:
C6H5CH[C6H4N(CH3)2]2
Número de CAS:
Peso molecular:
330.47
Beilstein/REAXYS Number:
2140506
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

technique(s)

microbe id | staining: suitable

mp

100-102 °C (lit.)

λmax

623 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C

InChI

1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3

InChI key

WZKXBGJNNCGHIC-UHFFFAOYSA-N

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Application

Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.

Biochem/physiol Actions

Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with little mutagenic or carcinogenic effect. LMG is one of the most commonly used reagents for presumptive blood test. It gives a characteristic green color in the presence of blood. LMG destroys DNA in the blood, therefore, the chances of DNA recovery and amplification is reduced or eliminated.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Los clientes también vieron

Mutagenicity and carcinogenicity in relation to DNA adduct formation in rats fed leucomalachite green.
Culp SJ
Mutation Research, 506-507, 55-63 (2002)
Evidence of aerosolised floating blood mist during oral surgery.
Ishihama K
Journal of Hospital Infection, 71(4), 359-364 (2009)
Becker, Ronald F. Becker, Aric W. Dutelle
Criminal Investigation (2012)
High incidence of blood exposure due to imperceptible contaminated splatters during oral surgery.
Ishihama K
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 66(4), 704-710 (2008)
Kevin J Farrugia et al.
Science & justice : journal of the Forensic Science Society, 51(3), 110-121 (2011-09-06)
This study investigates the optimisation of peroxidase based enhancement techniques for footwear impressions made in blood on various fabric surfaces. Four different haem reagents: leuco crystal violet (LCV), leuco malachite green (LMG), fluorescein and luminol were used to enhance the

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