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Merck

08982

Supelco

Sodium metabisulfite

analytical standard

Sinónimos:

E223, Sodium disulfite, Sodium pyrosulfite

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About This Item

Fórmula lineal:
Na2S2O5
Número de CAS:
Peso molecular:
190.11
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
E Number:
E223
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥98.0% (iodometric, RT)

shelf life

limited shelf life, expiry date on the label

mp

>300 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg
thiosulfate (S2O32-): ≤500 mg/kg

cation traces

As: ≤0.5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

[Na+].[Na+].[O-]S(=O)S([O-])(=O)=O

InChI

1S/2Na.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2

InChI key

HRZFUMHJMZEROT-UHFFFAOYSA-L

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General description

Sodium metabisulfite is primarily used as an antioxidant and antimicrobial agent in a wide variety of foods and drugs. It is also used as the main additive in the prevention of melanosis in shrimp.

Application

Sodium metabisulfite may be used as an antioxidant which when added to anesthetic formulations serves to minimize epinephrine oxidation in the quantification of epinephrine in dental anesthetic solutions by capillary electrophoresis. Sodium metabisulfite may also be used as a standard in the determination of catecholamines in human plasma by high-performance liquid chromatography with electrochemical detection.

Analysis Note

metal trace analysis: corresponds to requirements

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

supp_hazards

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Determination of catecholamines in human plasma by high-performance liquid chromatography with electrochemical detection.
Raggi MA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 730(2), 201-211 (1999)
Standardization of sodium metabisulfite solution concentrations and immersion time for farmed shrimp Litopenaeus vannamei.
Andrade LTD, et al.
Ciencia Rural, 45(3), 499-504 (2015)
The molecular mechanisms of sodium metabisulfite on the expression of KATP and L-Ca2+ channels in rat hearts.
Zhang Q, et al.
Regulatory Toxicology and Pharmacology, 72(3), 440-446 (2015)
Quantitative assay for epinephrine in dental anesthetic solutions by capillary electrophoresis.
Kranack A and Chen DY
Analyst, 123(7), 1461-1463 (1998)
Jeffrey N Hemenway et al.
Journal of pharmaceutical sciences, 101(9), 3305-3318 (2012-05-23)
A 2,4-dinitrophenylhydrazine (DNPH) precolumn derivatization high-performance liquid chromatography-ultraviolet detection (HPLC-UV) method was developed to quantify levels of formaldehyde and acetaldehyde in polyethylene glycol (PEG) solutions. Formic acid and acetic acid were quantified by HPLC-UV. Samples of neat and aqueous PEG

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