07260

6-Aminohexanoic acid

≥98.5% (NT)

• Sinónimos: 6-Aminocaproic acid, 6-ACA, Aca, Acp, Aha, Ahx, acikaprin, afibrin, amicar, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA
• Fórmula lineal: H₂N(CH₂)₅CO₂H
• Número de CAS: 60-32-2
• Peso molecular: 131.17
• Beilstein: 906872
• Número CE: 200-469-3
• Número MDL: MFCD00008238
• Código UNSPSC: 12352202
• ID de la sustancia en PubChem: 329748386
• NACRES: NA.77

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98.5% (NT)
• mp: 207-209 °C (dec.) (lit.)
• cadena SMILES: NCCCCCC(O)=O
• InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
• Clave InChI: SLXKOJJOQWFEFD-UHFFFAOYSA-N
• Información sobre el gen: human ... PLAT(5327) , PLG(5340)

Descripción

Descripción general

6-Aminohexanoic acid, or 6-aminocaproic acid, acts as an inhibitor of serine proteases. It shares structural similarities with the natural amino acid lysine but lacks an α-amino group.

Aplicación

6-Aminohexanoic acid has been used as a component of the growth medium for tenogenic differentiation of mesenchymal stem cells. It has also been used in the preparation of modified graphene quantum dots.

Acciones bioquímicas o fisiológicas

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Otras notas

Improves solubilization of membrane proteins in electrophoresis

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 404.6 - 408.2 °F
• Punto de inflamabilidad (°C): 207 - 209 °C
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves