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Merck

30-4310

Sigma-Aldrich

Ácido trifluoroacético

SAJ special grade, ≥99.0%

Sinónimos:

TFA

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About This Item

Fórmula lineal:
CF3COOH
Número de CAS:
Peso molecular:
114.02
Beilstein/REAXYS Number:
742035
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:

grade

SAJ special grade

vapor density

3.9 (vs air)

vapor pressure

97.5 mmHg ( 20 °C)

assay

≥99.0%

form

liquid

availability

available only in Japan

refractive index

n20/D 1.3 (lit.)

pH

1 (20 °C, 1 g/L)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

solubility

H2O: soluble

density

1.489 g/mL at 20 °C (lit.)

SMILES string

OC(C(F)(F)F)=O

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

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Application


  • New fabric phase sorptive extraction for nondestructive analysis of heritage textile samples.: This study introduces a novel extraction method utilizing trifluoroacetic acid for analyzing heritage textiles without causing damage. The technique improves the efficiency and accuracy of detecting and quantifying analytes in historical fabrics (Tanasescu et al., 2024).

  • Alpibectir: Early Qualitative and Quantitative Metabolic Profiling from a First Time in Human Study by Combining (19)F-NMR, (1)H-NMR and HRMS Analyses.: This research employs trifluoroacetic acid in metabolic profiling to enhance the resolution and accuracy of NMR and HRMS analyses, providing critical insights into the early stages of drug metabolism (Weston et al., 2024).

  • Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns.: The use of trifluoroacetic acid in preparing stationary phase gradients significantly improves the performance and stability of C8 columns in liquid chromatography, optimizing the separation of complex mixtures (Cecil et al., 2024).

  • Optimization of Cyanocobalamin (Vitamin B(12)) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles.: This article details the use of trifluoroacetic acid in the optimization process of sorbing vitamin B12 onto nanoparticles, enhancing the efficacy of nutrient delivery systems (Flieger et al., 2024).

  • Development, Validation, and Application of High-Performance Liquid Chromatography with Diode-Array Detection Method for Simultaneous Determination of Ginkgolic Acids and Ginkgols in Ginkgo biloba.: Trifluoroacetic acid is utilized in this method development for HPLC, enabling accurate and simultaneous determination of multiple compounds in Ginkgo biloba extracts (Boateng et al., 2024).

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

>212.0 °F - Pensky-Martens closed cup

flash_point_c

> 100 °C - Pensky-Martens closed cup


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