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Key Documents

MABF711

Sigma-Aldrich

Anti-CD54 (ICAM-1) Antibody (human), APC, clone 15.2

clone 15.2, from mouse

Sinónimos:

Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD antigen CD54

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

Allophycocyanin conjugate

antibody form

purified antibody

antibody product type

primary antibodies

clone

15.2, monoclonal

species reactivity

human

packaging

pkg of 5 μL (0.5 μg/test)

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ICAM1(3383)

General description

The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.
This mouse monoclonal antibody Anti-CD54 (ICAM-1) (human), APC, clone 15.2 validated for use in western blotting, IHC & Flow Cytometry for the detection of CD54 (ICAM-1).

Quality

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg of this antibody detected CD54 (ICAM-1) in one million human peripheral blood monocytes.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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