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MAB1974

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Anti-Integrin β3 Antibody, clone BB10

clone BB10, Chemicon®, from mouse

Sinónimos:

CD61

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

BB10, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

suitability

not suitable for immunohistochemistry (Paraffin)

NCBI accession no.

NM_000212.2

UniProt accession no.

P05106

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB3(3690)

Specificity

Reacts with the beta-3 subunit of the integrin family, including GPIIIa of platelets. Recognized an extracellular epitope of beta-3.

Immunogen

Partially purified platelet glycoprotein IIb/lIIa complex.

Application

Anti-Integrin β3 Antibody, clone BB10 is an antibody against Integrin β3 for use in WB, IC, IH.
Immunoblotting: 1:1000 (Ylanne et al., 1988, 1990). The antibody is most effective when used against non-reduced samples.

immunohistochemistry (indirect immunofluorescence)1:200 - 1:400. (Ylanne et al., 1988).

Does not work on paraffin embedded sections.

Final working dilutions must be determined by end user.

Physical form

Format: Purified
Purified immunoglobulin. In PBS with 1% BSA and 0.1% sodium azide.

Storage and Stability

Maintain between 2 and 8°C up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Descripción
Precios

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Gwendolyn F Elphick et al.
Blood, 113(17), 4078-4085 (2009-02-27)
Integrin-mediated cell migration is central to many biologic and pathologic processes. During inflammation, tissue injury results from excessive infiltration and sequestration of activated leukocytes. Recombinant human activated protein C (rhAPC) has been shown to protect patients with severe sepsis, although
D Seger et al.
The Journal of biological chemistry, 276(20), 16998-17006 (2001-03-30)
Phosphorylation of vitronectin (Vn) by casein kinase II was previously shown to occur at Thr50 and Thr57 and to augment a major physiological function of vitronectin-cell adhesion and spreading. Here we show that this phosphorylation increases cell adhesion via the
M A Scragg et al.
Infection and immunity, 67(4), 1837-1843 (1999-03-20)
Cell surface integrins mediate interactions between cells and their extracellular matrix and are frequently exploited by a range of bacterial pathogens to facilitate adherence and/or invasion. In this study we examined the effects of Porphyromonas gingivalis proteases on human gingival
John C Morrison
Transactions of the American Ophthalmological Society, 104, 453-477 (2007-05-02)
To demonstrate that specific distributions of integrin-based focal mechanoreceptors exist in primate optic nerve heads, suitable for translating stress and strain into the cellular responses of glaucomatous optic neuropathy. Normal human (N = 20) and rhesus monkey (N = 14)
Vincent Sarrazy et al.
Cardiovascular research, 102(3), 407-417 (2014-03-19)
Pathological tissue remodelling by myofibroblast contraction is a hallmark of cardiac fibrosis. Myofibroblasts differentiate from cardiac fibroblasts under the action of transforming growth factor-β1 (TGF-β1), which is secreted into the extracellular matrix as a large latent complex. Integrin-mediated traction forces
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