385898

Hsp90, Human

Hsp90, Human, is a ~90 kDa heat shock protein that is constitutively expressed and resides in the cytoplasm. It exists as a dimer and binds to several other cellular proteins.

• Sinónimos: Hsp90 chaperone
• UNSPSC Code: 12352202
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥90% (SDS-PAGE)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Descripción

General description

Native, human Hsp90. A ~90 kDa heat shock protein that is constitutively expressed and resides in the cytoplasm. It exists as a dimer and binds to other cellular proteins such as p60^v-src, steroid receptors, heme-regulated protein kinase, actin, and tubulin. Binds to histones with high affinity and induces chromatin condensation.

Native, human Hsp90. An ~90 kDa heat shock protein constitutively expressed and residues in the cytoplasm. It exists as a dimer and binds to other cellular proteins such as p60^v-src, steroid receptors, heme-regulated protein kinase, actin, and tubulin. Binds to histones with high affinity and induces chromatin condensation.

Warning

Toxicity: Standard Handling (A)

Physical form

In 100 mM NaCl, 50 mM Tris-HCl, 1 mM DTT, pH 7.5.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Kim, H.R., et al. 1999. J. Biochem. 126, 1025.Schnaider, T., et al. 1999. Life Sci. 65, 2417.Welch, W.J., et al. 1982. J. Biol. Chem. 257, 14949.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable