3741

Hemin Chloride

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

• Sinónimos: Hemin Chloride
• Número de CAS: 16009-13-5
• Número MDL: MFCD00010726
• Código UNSPSC: 12352202
• NACRES: NA.21

Propiedades

• Nivel de calidad: 100
• descripción: Merck USA index - 14, 4644
• Formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: dark purple
• solubilidad: 0.1-1.0 M NaOH: soluble; 1 N NH₄OH: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: 15-25°C
• InChI: 1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2
• Clave InChI: GGIDWJQWCUJYRY-UHFFFAOYSA-L

Descripción

Descripción general

Iron containing compound of porcine origin that can induce H₂O₂-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions. Induces heme-oxygenase-1 activity and reduces renal injury induced by mercuric compounds.

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

Aplicación

• Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: Discusses the therapeutic potentials of hemin chloride in neurological disorders, highlighting its role in mitigating cytotoxic effects associated with genetic mutations, significant for advancing neurodegenerative disease treatments (Hirayanagi K et al., 2021).


• Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: Demonstrates the application of hemin chloride in enhancing signal detection in spectroscopic analysis, important for improving analytical methods in environmental and food sciences (López-Castaños KA et al., 2020).

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Unstable in solution; reconstitute just prior to use.

Nota de análisis

homogeneous by TLC

Otras notas

Yonega, R., et al. 2000. Toxicol. Lett.116, 223.
Funanage, V.L., et al. 1989. J. Cell. Physiol.141, 591.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable