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Key Documents

324504

Millipore

EDTA

ULTROL® Grade, 500 mM Solution, pH 8.0

Sinónimos:

EDTA, 500 mM Solution, pH 8.0, ULTROL® Grade

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About This Item

Fórmula empírica (notación de Hill):
C10H16N2O8
Número de CAS:
60-00-4
Peso molecular:
292.24
MDL number:
MFCD00003541
UNSPSC Code:
12352107
NACRES:
NA.25

Quality Level

100

form

solution

reaction suitability

reagent type: chelator

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

concentration

500 mM

color

colorless to pale yellow

pH

8

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

Categorías relacionadas

General description

A useful agent for radioimmunoimaging.
Ethylenediaminetetraacetic acid (EDTA) is a metal chelating agent, which is used in treating patients with heavy-metal poisonings like lead or mercury. It is also used to minimize the non-specific serum protein interactions in enzyme immunoassays. Due to its ability to inhibit protein agglutination, it is useful to make blood/plasma samples and in immunoanalysis to detect CD3 cells. EDTA combines with buffers or ionic salts to stimulate the immune cells in the blood samples. It is used in multiple aspects to treat and analyze psoriasis. EDTA functions as an antioxidant to combat psoriasis, while it is also used to understand the disease at a molecular level.

Application

EDTA, 500 mM Solution, pH 8.0, ULTROL® Grade has been used along with phosphate buffer saline (PBS) for cell disruption to harvest crypts in situ hybridization of nematodes. It has also been used as a component of isoelectric focusing solution (IEF) to resuspend myofibrils for protein studies.

Warning

Toxicity: Irritant (B)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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M P Richards et al.
Journal of chromatography, 402, 243-256 (1987-07-31)
Reversed-phase high-performance liquid chromatography (RP-HPLC) was used to isolate, characterize and quantitate liver and kidney metallothionein (MT) isoforms from a variety of animal species. The isoMTs were eluted from a radially compressed C18 column with a neutral sodium phosphate buffer
Amreen Sunil et al.
Cureus, 13(7), e16424-e16424 (2021-07-20)
Psoriasis is a long-term, autoimmune inflammatory condition characterized by red, scaly plaques that can range from a few patches to total skin coverage. Over the past 60 years, and more recently, the metal-chelating agent ethylenediaminetetraacetic acid (EDTA) has proven increasingly
Krishnan MohanKumar et al.
American journal of physiology. Gastrointestinal and liver physiology, 318(4), G705-G716 (2020-02-25)
Anemia is a frequent diagnosis in critically ill infants, but the clinical implications of severe anemia in these patients remain unclear. In this study, we examined preweaned mice to investigate the effects of severe anemia during early infancy on gut
Walter E Knight et al.
STAR protocols, 2(4), 100912-100912 (2021-11-11)
When cultured under typical conditions, human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are structurally and functionally immature. We have previously demonstrated that culture of hiPSC-CMs in maturation medium containing fatty acids, in combination with culture on micropatterned surfaces, produces cells that

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