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Key Documents

219421

Sigma-Aldrich

Cathepsin L Inhibitor I

The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sinónimos:

Cathepsin L Inhibitor I, Z-FF-FMK

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About This Item

Fórmula empírica (notación de Hill):
C27H27FN2O4
Número de CAS:
Peso molecular:
462.51
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

color

white

solubility

DMSO: 20 mM

shipped in

ambient

storage temp.

−20°C

General description

A potent, cell-permeable and irreversible inhibitor of cathepsin L.
A potent, cell-permeable, and irreversible inhibitor of Cathepsin L (Cat. No. 219402).

Biochem/physiol Actions

Cell permeable: yes
Primary Target
cathepsin L
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Phe-Phe-CH₂F

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Analysis Note

single spot by TLC

Other Notes

Ravanko, K., et al. 2004. Cancer Res.64, 8831.
Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.
Shaw, E., et al. 1993. FEBS Lett.334, 340.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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