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Merck
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Key Documents

16-107

Sigma-Aldrich

Anti-PI3 Kinase Antibody, p85 Protein, agarose conjugate, 200 µg

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable

NCBI accession no.

NM_181504.2
NM_181523.1
NM_181524.1

UniProt accession no.

P27986

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PIK3R1(5295)

General description

Anti-PI 3-Kinase antibody (06-195) covalently coupled to protein A-agarose by dimethyl-pimelimidate.

Application

Anti-PI3 Kinase Antibody, p85, agarose conjugate detects level of PI3 Kinase & has been published & validated for use in IP.

Features and Benefits

Format: Gel Immobilized

Quality

routinely evaluated by immunoprecipitating PI 3-Kinase from RIPA lysate of EGF-stimulated human A431 carcinoma cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.
Rabinovsky, R; Pochanard, P; McNear, C; Brachmann, SM; Duke-Cohan, JS; Garraway, LA; Sellers, WR
Molecular and cellular biology null
Thomas A Blair et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1681-1688 (2014-06-07)
Platelet hyperactivity is a contributing factor in the pathogenesis of cardiovascular disease and can be induced by elevated levels of circulating growth factors, such as insulin-like growth factor-1 (IGF-1). IGF-1 is a primer that cannot stimulate platelet activation by itself
Timothy J Thauland et al.
Frontiers in immunology, 10, 753-753 (2019-04-30)
Gain-of-function variants in p110δ, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K) expressed in lymphocytes, cause activated PI3-kinase δ syndrome (APDS), a primary immunodeficiency that is characterized by recurrent infections, viremia, lymphadenopathy, and autoimmunity. The mechanism of autoimmunity in APDS has
Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle.
McCurdy, CE; Davidson, RT; Cartee, GD
American Journal of Physiology. Endocrinology and Metabolism null

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