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V-017

Supelco

Nicotinic acid

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Nicotinic acid, Vitamin B3, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid

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About This Item

Fórmula empírica (notación de Hill):
C6H5NO2
Número de CAS:
59-67-6
Peso molecular:
123.11
Beilstein:
109591
Número CE:
200-659-6
Número MDL:
MFCD00006391
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329828960
NACRES:
NA.24

grado

certified reference material

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

236-239 °C (lit.)

densidad

0.791 g/cm3 at 20 °C

aplicaciones

clinical testing
clinical testing

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

Clave InChI

PVNIIMVLHYAWGP-UHFFFAOYSA-N

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Descripción general

Nicotinic acid, also known as niacin, is a water-soluble vitamin of the B complex and essential human nutrient. Niacin deficiency, often the result of impaired nutritional status associated with conditions ranging from malnutrition to chronic alcoholism, is monitored in patient plasma samples by HPLC. This Certified Spiking Solution® is suitable for use as a starting material in the preparation of linearity standards, calibrators or controls in a variety of testing applications from diagnostic testing of niacin deficiency by HPLC to quality control testing of niacin-based pharmaceutical preparations, dietary supplements, or fortified foods.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Malte Lohölter et al.
Archives of animal nutrition, 67(3), 202-218 (2013-06-08)
The objective of this study was to investigate the effects of niacin and dietary concentrate proportion on body temperature, ruminal pH and milk production of dairy cows. In a 2 × 2 factorial design, 20 primiparous Holstein cows (179 ±
Ehab Haj Ali et al.
The West Virginia medical journal, 109(1), 12-14 (2013-02-19)
Niacin is an effective lipid-lowering agent which occasionally may cause hepatic failure. Liver enzymes are periodically tested during niacin therapy to assess for hepatic injury. We report a case of suppressed synthesis of hepatically derived coagulation factors and other liver
Antonio F Santidrian et al.
The Journal of clinical investigation, 123(3), 1068-1081 (2013-02-22)
Despite advances in clinical therapy, metastasis remains the leading cause of death in breast cancer patients. Mutations in mitochondrial DNA, including those affecting complex I and oxidative phosphorylation, are found in breast tumors and could facilitate metastasis. This study identifies
Amandine Girousse et al.
PLoS biology, 11(2), e1001485-e1001485 (2013-02-23)
When energy is needed, white adipose tissue (WAT) provides fatty acids (FAs) for use in peripheral tissues via stimulation of fat cell lipolysis. FAs have been postulated to play a critical role in the development of obesity-induced insulin resistance, a
Patrick M Moriarty et al.
Journal of clinical lipidology, 7(2), 140-146 (2013-02-19)
Niacin, or vitamin B3, when used in high doses can significantly improve the levels of all major lipoproteins. Despite these benefits, the use of niacin is greatly limited secondary to benign yet bothersome cutaneous flushing primarily involving the face and
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