T-078

3,3′,5′-Triiodo-L-thyronine-13C6 (reverse T3-13C6)

100 μg/mL in methanol with 0.1N NH₃, ampule of 1 mL, certified reference material, Cerilliant^®

• Sinónimos: 3,3′,5′-Triiodo-L-thyronine-¹³C₆ solution
• Fórmula empírica (notación de Hill): ¹³C₆C₉H₁₂I₃NO₄
• Número de CAS: 1786403-77-7
• Peso molecular: 656.93
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: (Snap-N-Spike^®)
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol with 0.1N NH₃
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• format: single component solution
• storage temp.: −20°C
• SMILES string: IC1=CC(O[13C]2=[13CH][13CH]=[13C](C[C@H](N)C(O)=O)[13CH]=[13C]2I)=CC(I)=C1O
• InChI: 1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)/t12-/m0/s1/i1+1,2+1,3+1,7+1,9+1,13+1
• Inchi Key: HZCBWYNLGPIQRK-CXGLLCBXSA-N

Descripción

General description

Reverse T3 or rT3 is a biologically inactive form of the thyroid hormone T3 and is produced in the body particularly during periods of stress. Under certain conditions such as fibromyalgia, liver disease, and chronic fatigue syndrome (CFS), more rT3 is produced which inhibits the desirable conversion of thyroxine (T4) to T3. This internal standard and Certified Spiking Solution^® is suitable for quantitation of reverse T3 serum concentrations by LC-MS/MS to monitor impact of these and other diseases on thyroid hormone levels.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F
• flash_point_c: 9.7 °C