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A-911

Supelco

7-Aminoflunitrazepam solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C16H14FN3O
Número de CAS:
34084-50-9
Peso molecular:
283.30
EC Number:
200-835-2
MDL number:
MFCD00798466
UNSPSC Code:
41116107
PubChem Substance ID:
329771032
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

FC1=CC=CC=C1C2=NCC(N(C)C3=CC=C(N)C=C23)=O

InChI

1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3

InChI key

LTCDLGUFORGHGY-UHFFFAOYSA-N

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General description

As a major metabolite of flunitrazepam, 7-aminoflunitrazepam is a biomarker for use of the parent drug. Flunitrazepam is an intermediate-acting benzodiazepine, typically used in the treatment of severe insomnia. This certified solution standard is suitable for numerous GC/MS or LC/MS testing applications in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.

Application

7-Aminoflunitrazepam solution is suitable for the in vivo identification, calibration, and quantification of analytes in analytical and R&D applications. It serves as an internal standard for quantifying 7-aminoflunitrazepam in human urine by polymeric monolith-based capillary liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).(Yu-Ru Wu, et al., 2018)

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Referencia del producto
Descripción
Precios

A-912

7-Aminoflunitrazepam solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-921

7-Aminoflunitrazepam-d7 solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-925

7-Aminoflunitrazepam-d7 solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-905

Benzodiazepine Internal Standard-3 solution, 0.5-1.0 mg/mL in acetonitrile, ampule of 1.0 mL, certified reference material, Cerilliant®

D-918

N-Desmethylflunitrazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-919

N-Desmethylflunitrazepam solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-925

N-Desmethylflunitrazepam-d4, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

F-907

Flunitrazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

F-915

Flunitrazepam-d7, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-140

3-Hydroxyflunitrazepam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

H-141

3-Hydroxyflunitrazepam-13C6 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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T1019

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(±)-11-nor-9-Carboxy-Δ9-THC solution 100 μg/mL in methanol, ampule of 1 mL, Cerilliant®

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Yi-Chi Ho et al.
Analytica chimica acta, 697(1-2), 1-7 (2011-06-07)
Despite the advantages of simplicity and high-throughput detection that matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has over other methods, quantitative analysis of low-molecular-weight analyte is hampered by interference from matrix-derived background noise and signal fluctuation due to the
Franz E Dussy et al.
International journal of legal medicine, 120(6), 323-330 (2005-10-13)
A high-performance liquid chromatography method for the determination of benzodiazepines and their metabolites in whole blood and serum using mass spectrometry (MS) and photodiode array (PDA) detection is presented. The combination of both detection types can complement each other and
Jeffery Hackett et al.
Forensic science international, 157(2-3), 156-162 (2005-06-16)
The forensic toxicology community has recognized flunitrazepam and its metabolite (7-aminoflunitrazepam) as compounds of concern for several years. In this procedure, the analytes were extracted from whole blood and urine onto single mode solid phase cartridges (butyl) using nitrazepam as
Mahaveer B Melwanki et al.
Talanta, 78(2), 618-622 (2009-02-11)
Dispersive liquid-liquid microextraction (DLLME) and liquid chromatography-electrospray-tandem mass spectrometry (LC-ES-MS/MS) procedure was presented for the extraction and determination of 7-aminoflunitrazepam (7-aminoFM2), a biomarker of the hypnotic flunitrazepam (FM2) in urine sample. The method was based on the formation of tiny
Masaru Terada et al.
Legal medicine (Tokyo, Japan), 5 Suppl 1, S96-S100 (2003-08-26)
A method for the determination of flunitrazepam (FNZ) and 7-aminoflunitrazepam (7-AFNZ) in human serum was developed with ion trap gas chromatography (GC)-tandem mass spectrometry. The 7-AFNZ was derivatizated with 50 microl trifluoroacetic anhydride (TFAA), 60 degrees C-20 min. EI mass
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