850345C

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

• Sinónimos: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Fórmula empírica (notación de Hill): C₃₆H₇₂NO₈P
• Número de CAS: 18194-24-6
• Peso molecular: 677.93
• Número MDL: MFCD33404495
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Ensayo: >99% (TLC)
• Formulario: liquid
• envase: pkg of 1 × 2.5 mL (850345C-25mg); pkg of 1 × 20 mL (850345C-500mg); pkg of 2 × 20 mL (850345C-1g); pkg of 2 × 4 mL (850345C-200mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 850345C
• concentración: 10 mg/mL (850345C-25mg); 25 mg/mL (850345C-1g); 25 mg/mL (850345C-200mg); 25 mg/mL (850345C-500mg)
• tipo de lípido: phospholipids; cardiolipins
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [P](=O)([O-])(OC[C@@H](OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1
• Clave InChI: CITHEXJVPOWHKC-UMSFTDKQSA-N

Descripción

Descripción general

Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicación

14:0 PC (DMPC) has been used in liposome preparation. It is also suitable for use:

• in the preparation of lipid bicelles for nuclear magnetic resonance (NMR) experiments
• in labeled vesicle preparation for fluorescence polarization measurements
• as internal standard (IS) for the quantitation of phosphatidylcholine (PC) by liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Envase

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-1g)

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850345C-500mg)

5 mL Clear Glass Sealed Ampule (850345C-200mg)

5 mL Clear Glass Sealed Ampule (850345C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Consejos de prudencia: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Órganos de actuación: Central nervous system, Liver,Kidney
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): does not flash
• Punto de inflamabilidad (°C): does not flash