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Merck

P73404

Sigma-Aldrich

Pyrrole-2-carboxaldehyde

98%

Sinónimos:

2-Formylpyrrole

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About This Item

Fórmula empírica (notación de Hill):
C5H5NO
Número de CAS:
Peso molecular:
95.10
Beilstein/REAXYS Number:
105745
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

crystals

bp

217-219 °C (lit.)

mp

43-46 °C (lit.)

storage temp.

2-8°C

SMILES string

[H]C(=O)c1ccc[nH]1

InChI

1S/C5H5NO/c7-4-5-2-1-3-6-5/h1-4,6H

InChI key

ZSKGQVFRTSEPJT-UHFFFAOYSA-N

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General description

Pyrrole-2-carboxaldehydesis a heterocyclic building blocks characterized by a pyrrole ring with a formylgroup attached at the 2-position used in the production of various biologicallyactive compounds. Highly functionalized pyrrole-2-carboxaldehydes have beenutilized as an intermediate in the creation of oligopyrrole macrocycles.

Application


  • Pyrimidine-based functional fluorescent organic nanoparticle probe for detection of Pseudomonas aeruginosa.: This study used pyrrole-2-carboxaldehyde to develop a fluorescent nanoparticle probe based on pyrimidine for detecting Pseudomonas aeruginosa, enhancing diagnostic capabilities in microbiology (Kaur G et al., 2015).


Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

224.6 °F - closed cup

flash_point_c

107 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Los clientes también vieron

Z H Chohan et al.
Chemical & pharmaceutical bulletin, 40(9), 2555-2556 (1992-09-01)
A new Schiff-base ligand N-(2'-pyrrylmethylidene)2-aminopyrimidine derived from the reaction of 2-amino pyrimidine and pyrrol-2-carboxaldehyde and its nickel(II), copper(II) and zinc(II) complexes have been synthesised and characterised on the basis of elemental analysis, molar conductance, infrared, electronic and proton nuclear magnetic
Investigation of optical and electrical properties of Pyrrole-2- carboxyldehyde (PCL) in PVA polymer matrix
Rana, Meenakshi and Devlal, et al.
Materials Today: Proceedings, 49, 3279-3282 (2022)
Huajian Zhu et al.
Organic letters, 13(10), 2792-2794 (2011-04-23)
A new synthetic protocol for efficient and regiospecifc assembly of indolizines and pyrido[1,2-a]indoles by coupling of substituted methyl bromides and alkynes with corresponding pyrrole-2-carboxaldehyde and 1H-indole-2-carboxaldehyde has been developed. Additionally, a possible mechanism for the reaction is proposed.
Michiko Kimoto et al.
Nucleic acids research, 35(16), 5360-5369 (2007-08-19)
Fluorescent labeling of nucleic acids is widely used in basic research and medical applications. We describe the efficient site-specific incorporation of a fluorescent base analog, 2-amino-6-(2-thienyl)purine (s), into RNA by transcription mediated by an unnatural base pair between s and
Aaron R Coffin et al.
The Journal of organic chemistry, 71(17), 6678-6681 (2006-08-12)
A regiocontrolled synthesis of 3,4-disubstituted pyrrole-2-carboxaldehydes was completed in two steps from acyclic starting materials. A Barton-Zard pyrrole synthesis between N-methoxy-N-methyl-2-isocyanoacetamide and alpha-nitroalkenes or beta-nitroacetates provided N-methoxy-N-methyl pyrrole-2-carboxamides (pyrrole Weinreb amides), which were converted into the corresponding pyrrole-2-carboxaldehydes by treatment

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