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Merck

P57204

Sigma-Aldrich

Pyridazine

98%

Sinónimos:

1,2-Diazabenzene, 1,2-Diazine, o-Diazine

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About This Item

Fórmula empírica (notación de Hill):
C4H4N2
Número de CAS:
Peso molecular:
80.09
Beilstein/REAXYS Number:
103906
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

refractive index

n20/D 1.524 (lit.)

bp

208 °C (lit.)

mp

−8 °C (lit.)

density

1.103 g/mL at 25 °C (lit.)

SMILES string

c1ccnnc1

InChI

1S/C4H4N2/c1-2-4-6-5-3-1/h1-4H

InChI key

PBMFSQRYOILNGV-UHFFFAOYSA-N

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General description

Pyridazine is a mono-basic 1,2-diazine compound, which is commonly prepared by the reaction of 1,4-dicarbonyls with hydrazines. Pyridazine ring is found in many herbicides like credazine, pyridatol and many pharmaceutical drugs like cefozopran, olaparib, talazoparib, and cadralazine.

Application

Pyridazine can be used:
  • As a building block to synthesize N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine derivatives as GSK-3 inhibitors.
  • As a starting material in the synthesis of pharmacologically important pyrrolo[1,2-b]pyridazine derivatives.
  • To prepare 1-(6-ethoxy-6-oxohexyl)pyridazin-1-ium bromide and 1-(2-bromoacetyl) pyridazinium bromide ionic liquids as corrosion inhibitors of steel under acidic conditions.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

185.0 °F - closed cup

flash_point_c

85 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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