Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

M14951

Sigma-Aldrich

5-Methoxyindole-2-carboxylic acid

97%

Sinónimos:

NSC 30927

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C10H9NO3
Número de CAS:
4382-54-1
Peso molecular:
191.18
Beilstein/REAXYS Number:
157478
EC Number:
224-487-6
MDL number:
MFCD00005614
UNSPSC Code:
12352100
PubChem Substance ID:
24896653
NACRES:
NA.22

Quality Level

100

assay

97%

mp

199-201 °C (lit.)

SMILES string

COc1ccc2[nH]c(cc2c1)C(O)=O

InChI

1S/C10H9NO3/c1-14-7-2-3-8-6(4-7)5-9(11-8)10(12)13/h2-5,11H,1H3,(H,12,13)

InChI key

YEBJVSLNUMZXRJ-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Reactant for preparation of:
  • Anticancer agents
  • A fluorescent small molecule probe for in vivo lipid imaging
  • Indoleamine 2,3-dioxygenase (IDO) inhibitors
  • Selective Dopamine D3 receptor ligands
  • 5-HT4 receptor ligands
  • Inhibitors of Mycobacterium tuberculosis pantothenate synthetase
  • Hypoxia selective cytotoxins
  • Potent antitumor bifunctional DNA alkylating agents

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Nathalie Sumien et al.
Behavioural brain research, 378, 112278-112278 (2019-10-21)
Stroke leads to devastating outcomes including impairments of sensorimotor and cognitive function that may be long lasting. New intervention strategies are needed to overcome the long-lasting effects of ischemic injury. Previous studies determined that treatment with 5-methoxyindole-2-carboxylic acid (MICA) conferred
Jinzi Wu et al.
Biochemical and biophysical research communications, 497(1), 444-450 (2018-02-16)
We previously reported that 5-methoxyindole-2-carboxylic acid (MICA) could induce preconditioning effect in the ischemic brain of rat. In the present study, we addressed the question of whether MICA could also trigger a postconditioning effect in ischemic stroke. To this end
Jinzi Wu et al.
Free radical biology & medicine, 113, 244-254 (2017-10-12)
The objective of this study was to investigate a possible role of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as a chemical preconditioning target for neuroprotection against ischemic injury. We used 5-methoxyindole-2-carboxylic acid (MICA), a reportedly reversible DLDH inhibitor, as the preconditioning agent
Luna Yamamori et al.
Zoological science, 34(3), 173-178 (2017-06-08)
Scyphozoa, Cubozoa and Hydrozoa are classes in the phylum Cnidaria that undergo metagenesis involving a dramatic morphological transition. In Scyphozoa and Cubozoa, when exposed to species- or strain-specific transition-inducing stimuli, asexually reproducing benthic polyps transform into sexually reproducing planktonic medusae.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico