D26202
3,5-Diamino-1,2,4-triazole
98%
Sinónimos:
Guanazole
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About This Item
Fórmula empírica (notación de Hill):
C2H5N5
Número de CAS:
Peso molecular:
99.09
Beilstein:
112467
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22
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Ensayo
98%
Formulario
solid
mp
202-205 °C (lit.)
cadena SMILES
Nc1n[nH]c(N)n1
InChI
1S/C2H5N5/c3-1-5-2(4)7-6-1/h(H5,3,4,5,6,7)
Clave InChI
PKWIYNIDEDLDCJ-UHFFFAOYSA-N
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Descripción general
3,5-Diamino-1,2,4-triazole, also known as Guanazole is a heterocyclic compound and is commonly used as a building block in the synthesis of gallium complexes of tert-butyl-substituted acyclic and cyclic compounds. It is also being investigated as a corrosion inhibitor for copper.
Aplicación
Inhibitor of DNA synthesis.
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Aquatic Chronic 2 - Repr. 2 - STOT RE 2
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Los clientes también vieron
W Suter et al.
Mutation research, 231(2), 251-264 (1990-08-01)
Guanazole and aphidicolin were chosen as candidates in the search for a selective, non-genotoxic inhibitor of DNA replication which could be used instead of hydroxyurea to measure DNA repair synthesis in rat hepatocyte primary cultures by liquid scintillation counting. The
A Sato et al.
Advances in enzyme regulation, 22, 231-241 (1984-01-01)
The data presented here show that while the non-heme iron subunit of ribonucleotide reductase is inhibited by IMPY, hydroxyurea and MAIQ, the mechanism of inhibition by hydroxyurea and IMPY is distinct from that for MAIQ. This difference in mechanisms is
V M Kolb et al.
Journal of molecular evolution, 38, 549-557 (1994-01-01)
Urazole is a five-membered heterocyclic compound which is isosteric with uracil's hydrogen-bonding segment. Urazole reacts spontaneoulsy with ribose (and other aldoses) to give a mixture of four ribosides: alpha and beta pyranosides and furanosides. This reaction occurs in aqueous solution
L Guennoun et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(1), 347-353 (2010-11-30)
The 3,5-diamino-1,2,4-triazole (guanazole) was investigated by vibrational spectroscopy and quantum methods. The solid phase FT-IR and FT-Raman spectra were recorded in the region 4000-400 cm(-1) and 3600-50 cm(-1) respectively, and the band assignments were supported by deuteration effects. The results
G R Gale et al.
Cancer treatment reports, 63(3), 449-456 (1979-03-01)
Each of three ribonucleoside diphosphate reductase inhibitors was used as a third drug in combination with selected antitumor platinum (Pt) agents and cyclophosphamide (CY) in the treatment of advanced L1210 leukemia in C57BL/6 x DBA/2 mice. Each was synergistic with
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