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Key Documents

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C117307

Sigma-Aldrich

Bromocyclopropane

99%

Sinónimos:

Cyclopropyl bromide

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About This Item

Fórmula empírica (notación de Hill):
C3H5Br
Número de CAS:
4333-56-6
Peso molecular:
120.98
Beilstein/REAXYS Number:
1900287
EC Number:
224-375-7
MDL number:
MFCD00001271
UNSPSC Code:
12352100
PubChem Substance ID:
24892372
NACRES:
NA.22

Quality Level

200

assay

99%

form

liquid

refractive index

n20/D 1.458 (lit.)

bp

69 °C (lit.)

density

1.51 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

BrC1CC1

InChI

1S/C3H5Br/c4-3-1-2-3/h3H,1-2H2

InChI key

LKXYJYDRLBPHRS-UHFFFAOYSA-N

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General description

Bromocyclopropane acts as a key intermediate in organic synthesis and a building block for constructing diverse chemical structures in drug development.

pictograms

Flame
GHS02

signalword

Danger

hcodes

H225

Hazard Classifications

Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

21.2 °F - closed cup

flash_point_c

-6 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificados de análisis (COA)

Lot/Batch Number
SDBB0723
0000290147
0000276657
STBL1293
STBK2285

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Mechanism-Driven Elaboration of an Enantioselective Bromocyclopropanation Reaction of Allylic Alcohols
S Taillemaud, et al.
Angewandte Chemie (International Edition in English), 127, 14314-14318 (2015)
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ChemMedChem, 6(1), 73-80 (2010-11-12)
Many new chemotherapeutic agents are under preclinical investigation and, despite efforts to more selectively target cancer cells, limitations such as toxicity and inherent resistance are often encountered. Therefore, alternative strategies are needed to treat cancer and overcome such limitations. We
Carmen Abate et al.
ChemMedChem, 7(10), 1847-1857 (2012-08-15)
σ(2) Receptor research is receiving increasing interest with regard to the potential of σ(2) proteins as targets for tumor therapy and diagnosis. Nevertheless, knowledge about the σ(2) receptor is far from conclusive. The paucity and modest affinity of known σ(2)
Carmen Abate et al.
Journal of medicinal chemistry, 57(8), 3314-3323 (2014-04-05)
Despite the promising potentials of σ2 receptors in cancer therapy and diagnosis, there are still ambiguities related to the nature and physiological role of the σ2 protein. With the aim of providing potent and reliable tools to be used in
Maria Laura Pati et al.
Pharmacological research, 117, 67-74 (2016-12-23)
A controversial relationship between sigma-2 and progesterone receptor membrane component 1 (PGRMC1) proteins, both representing promising targets for the therapy and diagnosis of tumors, exists since 2011, when the sigma-2 receptor was reported to be identical to PGRMC1. Because a
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