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Merck

B103500

Sigma-Aldrich

Butyric acid

≥99%

Sinónimos:

1-Propanecarboxylic acid, Ethylacetic acid, Propylformic acid, n-Butanoic acid, n-Butyric acid

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About This Item

Fórmula lineal:
CH3CH2CH2COOH
Número de CAS:
Peso molecular:
88.11
Beilstein/REAXYS Number:
906770
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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vapor density

3.04 (vs air)

Quality Level

vapor pressure

0.43 mmHg ( 20 °C)

assay

≥99%

form

liquid

autoignition temp.

824 °F

expl. lim.

10 %

technique(s)

HPLC: suitable

refractive index

n20/D 1.398 (lit.)

pH

2 (25 °C, 10 g/L)
3 (20 °C, 10 g/L)

bp

162 °C (lit.)

mp

−6-−3 °C (lit.)

solubility

water: soluble 10 g/L at 20 °C

density

0.964 g/mL at 25 °C (lit.)

SMILES string

CCCC(O)=O

InChI

1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)

InChI key

FERIUCNNQQJTOY-UHFFFAOYSA-N

Gene Information

human ... HDAC1(3065)

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General description

Butyric acid, also known as Ethylacetic acid, is a short-chain volatile fatty acid that is commonly used as a precursor in the synthesis of ethyl butyrate and butyl butyrate. [1]

Application

Butyric acid may be used as a starting material in the preparation of 4-heptanone.[2]

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

161.6 °F - closed cup

flash_point_c

72 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Multifunctional acyloxyalkyl ester prodrugs of 5-aminolevulinic acid in cancer cell lines inhibited the proteasome and induced apoptosis and heme synthesis. The most potent prodrug was butyryloxymethyl 5-amino-4-oxopentanoate (1a). The metabolically released formaldehyde from the prodrugs was the dominant factor affecting

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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. 안녕하세요. Butyric acid (B103500-5mL) Cell treat 사용 여부에 대한 문의 드립니다.

    1 answer
    1. The suitability for cell culture has not been assessed for product B103500. There certainly is a field of research where this product has been used for cell treatment based applications. Please see the citations listed below for more information.

      Íñiguez-Gutiérrez L, Godínez-Méndez LA, Fafutis-Morris M, Padilla-Arellano JR, Corona-Rivera A, Bueno-Topete MR, Rojas-Rejón ÓA, Delgado-Rizo V. Physiological concentrations of short-chain fatty acids induce the formation of neutrophil extracellular traps in vitro. Int J Immunopathol Pharmacol. 2020 Jan-Dec;34:2058738420958949. doi: 10.1177/2058738420958949. PMID: 33373277; PMCID: PMC7783874.

      Juliana Coronel, Sandra Klausing, Christoph Heinrich, Thomas Noll, Alvio Figueredo-Cardero, Leda R. Castilho, Valeric acid supplementation combined to mild hypothermia increases productivity in CHO cell cultivations, Biochemical Engineering Journal, Volume 114, 2016, Pages 101-109, ISSN 1369-703X, https://doi.org/10.1016/j.bej.2016.06.031.

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