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Merck

A79604

Sigma-Aldrich

4-Aminosalicylic acid

99%, for peptide synthesis

Sinónimos:

4-Amino-2-hydroxybenzoic acid, PAS

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About This Item

Fórmula lineal:
H2NC6H3-2-(OH)CO2H
Número de CAS:
Peso molecular:
153.14
Beilstein/REAXYS Number:
473071
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

product name

4-Aminosalicylic acid, 99%

Quality Level

assay

99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

white to beige

mp

135-145 °C (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(C(O)=O)c(O)c1

InChI

1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)

InChI key

WUBBRNOQWQTFEX-UHFFFAOYSA-N

Gene Information

human ... PTPN1(5770)

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Application

4-Aminosalicylic acid (4-ASA) can be used in the synthesis of:
  • Azo derivatives of 4-ASA with anti-inflammatory effects.
  • Ammonium 4-aminosalicylate salt polymorphs which are used as pharmaceutical ingredients.
  • Salicylic acid-triazole analogs which are used as quorum sensing inhibitors against Pseudomonas aeruginosa.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Synthesis of azo derivatives of 4-aminosalicylic acid.
Zhao ZB, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 18(6), 639-642 (2007)
Design, Synthesis and Biological Evaluation of Triazole-Containing 2-Phenylindole and Salicylic Acid as Quorum Sensing Inhibitors Against Pseudomonas aeruginosa.
Srinivasarao S, et al.
ChemistrySelect, 3(32), 9170-9180 (2018)
Polymorphic ammonium salts of the antibiotic 4-aminosalicylic acid.
Andre V, et al.
Crystal Growth & Design, 12(6), 3082-3090 (2012)
Maria João Forjaz et al.
Movement disorders : official journal of the Movement Disorder Society, 30(4), 545-551 (2014-12-30)
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Tian-Loon Lee et al.
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To determine the incidence of intraocular pressure (IOP) spikes within the first 30 minutes after sequential argon-Nd:YAG laser peripheral iridotomy (LPI) in patients with angle closure and to explore risk factors for their occurrence. A total of 428 consecutive eyes

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