A47052
6-Aminochrysene
95%
Sinónimos:
6-Chrysenamine
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About This Item
Fórmula empírica (notación de Hill):
C18H13N
Número de CAS:
Peso molecular:
243.30
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Productos recomendados
Quality Level
assay
95%
form
solid
mp
209-211 °C (lit.)
SMILES string
Nc1cc2c3ccccc3ccc2c4ccccc14
InChI
1S/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2
InChI key
KIVUHCNVDWYUNP-UHFFFAOYSA-N
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Application
Produces tumors in mice.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Los clientes también vieron
K B Delclos et al.
Cancer research, 47(23), 6272-6277 (1987-12-01)
6-Nitrochrysene (NC) and 6-aminochrysene (AC) have been shown to be potent lung and liver carcinogens when administered in multiple i.p. doses to preweanling mice. 1,6-Dinitropyrene has been shown to be a strong hepatocarcinogen but a weak lung carcinogen in this
S Lahmy et al.
Toxicology, 29(4), 345-356 (1984-02-01)
By microspectrofluorimetry on single living cells (murine fibroblasts 3T3), we have obtained monoexponential decreases of fluorescence intensity for benzo[a]pyrene (B[a]P) and 6-aminochrysene (6a-chrysene) metabolism. These kinetics are characteristics of B[a]P and 6a-chrysene metabolism and histograms can be drawn from the
Yi Zhang et al.
Environmental toxicology and chemistry, 25(7), 1920-1925 (2006-07-13)
Chrysene is one of the basic polycyclic aromatic hydrocarbons that are toxic environmental pollutants. The photoproducts of 6-aminochrysene (6AC) include 5,6-chrysenequinone (5,6-CQ) along with some minor products. In this study, cytotoxicity and genotoxicity of 6AC and 5,6-CQ to a human
F K Friedman et al.
Pharmacology, 31(4), 194-202 (1985-01-01)
The microsomal cytochrome P-450-dependent aryl hydrocarbon hydroxylase is important in the detoxification of polycyclic hydrocarbons as well as their activation to cytotoxic or carcinogenic derivatives. We have studied compounds that can modify the activity of this enzyme system. Three types
T Marczylo et al.
Mutagenesis, 9(3), 233-239 (1994-05-01)
6-Aminochrysene was converted into mutagen(s), in the Ames test in the presence of Aroclor 1254-induced hepatic S9, microsomal and cytosolic fractions, the first being the least and the last the most efficient activation system. The cytosolic activation of 6-aminochrysene decreased
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