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Merck
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Key Documents

934097

Sigma-Aldrich

Ovine collagen

methacrylate functionalized, low endotoxin

Sinónimos:

CollOvine MA

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About This Item

Número de CAS:
UNSPSC Code:
12352202
NACRES:
NA.28

Quality Level

form

powder

impurities

Bioburden, none detected
≤0.1 EU/mg Endotoxin

color

white to off-white

functional group

methacrylate

storage temp.

2-8°C

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General description

Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Methacrylate functionalized collagen is a polymerizable hydrogel material derived from low endotoxin ovine collagen. The addition of photocrosslinkable methacrylate functional groups allows the photopolymerization of biocompatible, biodegradable, and non-immunogenic hydrogels which can encapsulate cells and be used in many biomedical applications. This methacrylate functionalized collagen is also a great alternative to other naturally derived collagens such as those derived from bovine or porcine.

Application

  • 3D bioprinting
  • Tissue engineering
  • Drug delivery
  • Regenerative medicine
  • Cell culture, encapsulation, expansion and differentiation

Features and Benefits

  • Certified Disease Free Sheep
  • 93-97% Type I Collagen
  • 3-7% Type III Collagen
  • 99% Purity
  • Prion Free

Legal Information

CollOvine is a trademark of OviGenex LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Collagen as Bioink for Bioprinting: A Comprehensive Review
Osidak E O, et al.
International Journal of Bioprinting, 6, 270-270 (2020)
Elizabeth E Antoine et al.
Tissue engineering. Part B, Reviews, 20(6), 683-696 (2014-06-14)
Type I collagen hydrogels have been used successfully as three-dimensional substrates for cell culture and have shown promise as scaffolds for engineered tissues and tumors. A critical step in the development of collagen hydrogels as viable tissue mimics is quantitative
Atiqah Salleh et al.
Biomedicines, 10(4), 816-816 (2022-04-24)
Tissue engineering products have grown rapidly as an alternative solution available for chronic wound and burn treatment. However, some drawbacks include additional procedures and a lack of antibacterial properties that can impair wound healing, which are issues that need to
Jana Stepanovska et al.
Biomedicines, 9(9), 1137-1137 (2021-09-29)
Bioprinting is a modern tool suitable for creating cell scaffolds and tissue or organ carriers from polymers that mimic tissue properties and create a natural environment for cell development. A wide range of polymers, both natural and synthetic, are used

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