913979

Biotin-Thalidomide

≥95%

• Sinónimos: N¹-(4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-N⁵-(15-oxo-19-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-14-azanonadecyl)glutaramide, Biotin-conjugated thalidomide, bio-Thal
• Fórmula empírica (notación de Hill): C₄₄H₆₄N₈O₁₃S
• Número de CAS: 2230857-87-9
• Peso molecular: 945.09
• NACRES: NA.22

Propiedades

• ligand: thalidomide
• Quality Level: 100
• assay: ≥95%
• form: powder
• storage temp.: −20°C
• SMILES string: O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3OCC(NCCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@](NC(N5)=O)([H])[C@]5([H])CS4)=O)=O)=O)=O)=O)NC1=O

Descripción

Application

Biotin-Thalidomide (bio-Thal) is a cereblon affinity probe for PROTAC^® and targeted protein degradation research. Bio-Thal can be used in cereblon (CRBN) binding and displacement assays for protein degrader validation experiments, CRBN ligand discovery, competition analyses, or where enrichment of CRBN complexes is required.

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Other Notes

The dTAG system for immediate and target-specific protein degradation

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable