905186

(9-Bromononyl)triphenylphosphonium bromide

• Sinónimos: Bromononane TPP mitochondrial tag, Mitochondria-targeting probe building block, Phosphonium lipocation tag
• Fórmula empírica (notación de Hill): C₂₇H₃₃Br₂P
• Número de CAS: 90052-38-3
• Peso molecular: 548.33
• UNSPSC Code: 12352200

Propiedades

• form: liquid
• storage temp.: 2-8°C
• InChI: 1S/C27H33BrP.BrH/c28-23-15-4-2-1-3-5-16-24-29(25-17-9-6-10-18-25,26-19-11-7-12-20-26)27-21-13-8-14-22-27;/h6-14,17-22H,1-5,15-16,23-24H2;1H/q+1;/p-1
• InChI key: ACKJFSDDEOFXHT-UHFFFAOYSA-M

Descripción

Application

Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This bromononane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria.

Other Notes

Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion

Targeting lipophilic cations to mitochondria

Photoswitchable polyfluorophores based on perylenemonoimide-dithienylethene conjugates as super-resolution MitoTrackers

Información de seguridad

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable