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Merck
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Key Documents

81381

Sigma-Aldrich

Poli(vinil alcohol)

Mw ~31,000

Sinónimos:

Poly(vinyl alcohol)

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About This Item

Fórmula lineal:
[-CH2CHOH-]n
Número de CAS:
9002-89-5
MDL number:
MFCD00081922
UNSPSC Code:
12352104
NACRES:
NA.23

form

crystals

Quality Level

200

mol wt

Mw ~31,000

extent of labeling

86.7-88.7 mol% hydrolysis
~630 polymerization

ign. residue

≤0.5%

viscosity

3.5-4.5 mPa.s, 4 % in H2O(20 °C)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

Mowiol® is a water soluble hydrocolloid mucoadhesive based on poly (vinyl alcohol). Mowiol® at pH 8.5 has a couple of advantages over other mounting media:
  • its a liquid when the sample is mounted and solidifies after several hours, forming a permanent bond between the coverslip and slide
  • fluorescence is stable when held in dark and at 4oC.

Application

Mowiol® is used as an embedding medium for preserving stained cell dishes in the study of siRNA array production of HeLa cells. Mowiol® is also reported to be used as a mounting medium in:
  • design of TSAR and its applications
  • detection of the secreted and cytoplasmic fractions of IpaB, IpaC and IpaD by lysozyme permeabilization
  • fluorescence recovery after photobleaching (FRAP).

Mowiol® may be used as a coating for sensors based on piezoelectric quartz crystals. Another probable use of Mowiol® is during the study of super fluorescence imaging of biocompatible carbon dots.

Legal Information

Mowiol is a registered trademark of Kuraray Europe GmbH

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Xiaofang Li et al.
Scientific reports, 7(1), 16495-16495 (2017-12-01)
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients is an unsolved issue. Here, we systematically analyzed the aberrant expression patterns of cervical cancer using RNA-Seq data from The Cancer Genome Atlas (TCGA). We incorporated gene profiling
Super-resolution fluorescence imaging of biocompatible carbon dots.
Lemenager G, et al.
Nanoscale, 6, 8614-8623 (2014)
Avgi Tsolou et al.
Life sciences, 232, 116562-116562 (2019-06-16)
Lung cancer is one of the main causes of cancer-related deaths worldwide and radiotherapy is a major treatment of choice. However, radioresistance is a main reason for radiotherapy failure or tumor relapse. Here, we investigated possible mechanisms associated with cancer
A Kondratskyi et al.
Cell death & disease, 5, e1193-e1193 (2014-04-26)
The growing number of studies suggested that inhibition of autophagy enhances the efficacy of Akt kinase inhibitors in cancer therapy. Here, we provide evidence that ML-9, a widely used inhibitor of Akt kinase, myosin light-chain kinase (MLCK) and stromal interaction
Cedric S Tremblay et al.
Nature communications, 9(1), 3535-3535 (2018-09-01)
Pre-leukemic stem cells (pre-LSCs) give rise to leukemic stem cells through acquisition of additional gene mutations and are an important source of relapse following chemotherapy. We postulated that cell-cycle kinetics of pre-LSCs may be an important determinant of clonal evolution
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