709492

(1S,4S,8S)-5-Benzyl-2-isobutyl-8-methoxy-1,8-dimethylbicyclo[2.2.2]octa-2,5-diene

97%

• Sinónimos: (1S,4S,8S) Carreira DOLEFIN Ligand
• Fórmula empírica (notación de Hill): C₂₂H₃₀O
• Número de CAS: 862499-50-1
• Peso molecular: 310.47
• MDL number: MFCD09265063
• UNSPSC Code: 12352112
• PubChem Substance ID: 329762875
• NACRES: NA.06

Propiedades

• Quality Level: 100
• assay: 97%
• form: liquid
• optical activity: [α]/D −84±5°, c = 0.5 in chloroform
• reaction suitability: reaction type: click chemistry
• refractive index: n20/D 1.522
• SMILES string: CO[C@@]1(C)C[C@@]2(C)C=C(Cc3ccccc3)[C@@H]1C=C2CC(C)C
• InChI: 1S/C22H30O/c1-16(2)11-19-13-20-18(12-17-9-7-6-8-10-17)14-21(19,3)15-22(20,4)23-5/h6-10,13-14,16,20H,11-12,15H2,1-5H3/t20-,21+,22-/m0/s1
• InChI key: ACWLDJOHMGJACE-BDTNDASRSA-N

Descripción

General description

(1S,4S,8S)-5-Benzyl-2-isobutyl-8-methoxy-1,8-dimethylbicyclo[2.2.2]octa-2,5-diene, an enantiopure diene ligand developed by Carreira, is most commonly used in asymmetric catalysis. It is generally prepared from commercially available (R)-carvone.

Application

Carreira DOLEFIN Ligands

(1S,4S,8S)-5-Benzyl-2-isobutyl-8-methoxy-1,8-dimethylbicyclo[2.2.2]octa-2,5-diene is mainly useful for the stereoselective synthesis of diarylmethine stereogenic centers.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable