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677418

Sigma-Aldrich

Hydroxyapatite

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

Sinónimos:

Calcium hydroxyphosphate, HAp, Hydroxylapatite

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About This Item

Fórmula lineal:
[Ca5(OH)(PO4)3]x
Número de CAS:
12167-74-7
Peso molecular:
502.31
Número CE:
235-330-6
Número MDL:
MFCD00010904
Código UNSPSC:
12352302
ID de la sustancia en PubChem:
24885371
NACRES:
NA.23
Ensayo:
≥97%
Formulario:
nanopowder
solid

Nivel de calidad

100

Ensayo

≥97%

Formulario

nanopowder
solid

superficie

>9.4 m2/g

tamaño de partícula

<200 nm (BET)

mp

1100 °C (lit.)

cadena SMILES

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

Clave InChI

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Descripción general

Hydroxyapatite(HA) belongs to the family of Ca apatite which resembles natural bone in both structure and chemical composition. It can be prepared by various techniques such as chemical precipitation, hydrothermal, electrospinning, and self-propagating combustion. It is widely used as an implant material for bone regeneration, a drug carrier, and a gene delivery system due to its bioactive and biocompatible nature.

Aplicación

Nanoscale hydroxyapatite particles can be used to prepare bone tissue engineering materials due to their slow biodegradability in situ, good osteoconductive and osteoinductive capabilities.

Poly (sodium 4-styrene sulfonate)-modified hydroxyapatite nanoparticles can be used as a drug carrier for vancomycin. Hydroxyapatite nanoparticles control the release of antibiotics after the implantation of a scaffold in the body.

Porous hydroxyapatite microspheres exhibit a high adsorptive capacity for heavy metals and can be used for the treatment of heavy metal contaminated water.

Características y beneficios

  • Bioactive and biocompatible
  • Good mechanical strength
  • Porous structure
  • Osteoconductive and osteointegrative properties

Información legal

Product of Engi-Mat Co.

Código de clase de almacenamiento

13 - Non Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
MKCV8701
MKCX0776
MKCW0988
MKCS9574
MKCV4489

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Furqan A Shah
Scientific reports, 10(1), 16662-16662 (2020-10-09)
Various compositional parameters are derived using intensity ratios and integral area ratios of different spectral peaks and bands in the Raman spectrum of bone. The [Formula: see text]1-, [Formula: see text]2-,[Formula: see text]3-, [Formula: see text]4 PO43-, and [Formula: see
Michiko Sato et al.
Biomaterials, 27(11), 2358-2369 (2005-12-13)
In order to improve orthopedic implant performance, the objective of this in vitro study was to synthesize nanocrystalline hydroxyapatite (HA) powders to coat titanium. HA was synthesized through a wet chemical process. The precipitated powders were either sintered at 1100
Deepak Bushan Raina et al.
Acta orthopaedica, 91(2), 126-132 (2019-11-05)
Background and purpose - Targeted delivery of drugs is important to achieve efficient local concentrations and reduce systemic side effects. We hypothesized that locally implanted synthetic hydroxyapatite (HA) particles can act as a recruiting moiety for systemically administered drugs, leading
Sang-Soo Kim et al.
Biomaterials, 27(8), 1399-1409 (2005-09-20)
Biodegradable polymer/bioceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. However, conventional methods for fabricating polymer/bioceramic composite scaffolds often use organic solvents (e.g., the solvent casting and particulate leaching (SC/PL)
Hydroxyapatite nanoparticles: a review of preparation methodologies
Ferraz MP, et al.
Journal of Applied Biomaterials & Biomechanics : JABB, 2(2), 74-80 (2004)
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