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541397

Sigma-Aldrich

10-Bromodecanoic acid

95%

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About This Item

Fórmula lineal:
Br(CH2)9CO2H
Número de CAS:
50530-12-6
Peso molecular:
251.16
MDL number:
MFCD00014388
UNSPSC Code:
12352100
PubChem Substance ID:
24878533
NACRES:
NA.22

Quality Level

100

assay

95%

reaction suitability

reagent type: linker

mp

38-41 °C (lit.)

functional group

bromo
carboxylic acid

SMILES string

OC(CCCCCCCCCBr)=O

InChI

1S/C10H19BrO2/c11-9-7-5-3-1-2-4-6-8-10(12)13/h1-9H2,(H,12,13)

InChI key

PGVRSPIEZYGOAD-UHFFFAOYSA-N

General description

10-Bromodecanoic acid can be prepared from 10-bromodecanol via oxidation.

Application

10-Bromodecanoic acid may be employed as an alkylcarboxylate chain source in the preparation of alkylcarboxylate-grafted polyethylenimine. It may also be used in the synthesis of :
  • 10-(methylsulfinyl)decanoic acid
  • 10-cyanodecanoic acid
  • (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)-decyl)triphenylphosphonium bromide
  • 11-thiastearic acid

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
02714LD
03414AB
27409DB
11504DA

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M D Rahman et al.
Journal of medicinal chemistry, 31(8), 1656-1659 (1988-08-01)
A variety of analogues of stearic acid in which one of the methylene groups was replaced by a sulfur atom were examined as inhibitors of growth and fatty acid biosynthesis in the trypanosomatid protozoan Crithidia fasciculata. The 8-, 9-, 10-
Fatemeh Soltani et al.
Artificial cells, nanomedicine, and biotechnology, 45(7), 1356-1362 (2016-11-01)
Poor water solubility of hydrophobic drugs is one of the major problems in pharmaceutical sciences. Herein, in order to address the poor solubility of crocetin, the 30% of primary amines of PAMAM G4 and PPI G4 were alkylated and evaluated
Reza K Oskuee et al.
The journal of gene medicine, 11(10), 921-932 (2009-07-28)
Various strategies have been examined to improve both transfection efficiency and cytotoxicity of polyethylenimine (PEI), a widely used polycationic nonviral gene vector. In the present study, we sought to improve PEI transfection efficiency by combining the osmotic burst mechanism for
Sara Ayatollahi et al.
The international journal of biochemistry & cell biology, 92, 210-217 (2017-10-17)
RNAi-based gene therapy has been recently considered as a promising approach against cancer. Targeted delivery of drug, gene or therapeutic RNAi-based systems to tumor cells is one of the important issues in order to reduce side effects on normal cells.
The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor,(10-oxo-10-(4-(3-thioxo-3 h-1, 2-dithiol-5-yl) phenoxy) decyl) triphenylphosphonium bromide (Ap39).
Le Trionnaire S, et al.
MedChemComm, 5(6), 728-736 (2014)
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