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Merck

419737

Sigma-Aldrich

6-Methoxyflavone

99%

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About This Item

Fórmula empírica (notación de Hill):
C16H12O3
Número de CAS:
Peso molecular:
252.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

solid

mp

163-165 °C (lit.)

functional group

ketone
phenyl

SMILES string

COc1ccc2OC(=CC(=O)c2c1)c3ccccc3

InChI

1S/C16H12O3/c1-18-12-7-8-15-13(9-12)14(17)10-16(19-15)11-5-3-2-4-6-11/h2-10H,1H3

InChI key

XZQLSABETMKIGG-UHFFFAOYSA-N

Gene Information

General description

6-Methoxyflavone is one of the methoxyflavone isolated form Pimelea decora. Synthesis of 6-methoxyflavone from p-dihydroxybenzene has been reported.

Application

6-Methoxyflavone may be employed in the following studies:
  • As internal standard for the analysis of polyphenolic content of in-vitro-cultured chestnut shoots.
  • Synthesis of biflavonoids, rac- and meso-6,6-dimethoxy-2,2-biflavanones.
  • As internal standard for the separation of phenolic compounds in the apricot tissue by HPLC.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Photohydrodimerization of 6-Methoxyflavone to 6, 6′-Dimethoxy-2, 2′-Biflavanones.
Chen A-H, et al.
J. Chin. Chem. Soc., 51(6), 1389-1394 (2004)
Sara Serra et al.
Foods (Basel, Switzerland), 9(10) (2020-10-18)
The rising interest in beneficial health properties of polyphenol compounds in fruit initiated this investigation about biochemical composition in peach mesocarp/exocarp. Biochemical evaluation of phenolic compounds and ascorbic acid were quantified through high-performance liquid chromatography (HPLC) in relation to three
Muhammad Shahid et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 1725-1733 (2017-10-01)
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose limiting side-effect of several commonly used chemotherapeutic agents (such as cisplatin) that profoundly impairs patient quality of life. Unfortunately, neither prophylactic strategies nor symptomatic treatments have proven useful in this condition. Flavonoids
J. L. Fernandez-Lorenzo et al.
Tree physiology, 19(7), 461-466 (2003-03-26)
The phenolic contents of eight in-vitro-cultivated chestnut clones (Castanea sativa Mill. and C. sativa x C. crenata Siebold & Zucc. hybrids) were analyzed both qualitatively and quantitatively. The aim of the work was to identify potential phenolic markers of: (i)
Pilar Errea et al.
Physiologia plantarum, 112(1), 135-141 (2001-04-25)
Graft compatibility has been studied in vitro using callus tissues of apricot (Prunus armeniaca) and different Prunus rootstocks to form scion/rootstock combinations with different degrees of graft compatibility. In these species, incompatibility is manifested by a breakdown of the trees

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