419656

N-Benzyl-2-nitro-1H-imidazole-1-acetamide

97%

• Sinónimos: 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide, Benzonidazol, N-Benzyl-2-nitroimidazol-1-yl-acetamide
• Fórmula empírica (notación de Hill): C₁₂H₁₂N₄O₃
• Número de CAS: 22994-85-0
• Peso molecular: 260.25
• MDL number: MFCD00243089
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866267
• NACRES: NA.22

Propiedades

• assay: 97%
• mp: 189-192 °C (lit.)
• solubility: methanol: soluble 50 mg/mL, clear, colorless to yellow
• functional group: amide; nitro; phenyl
• SMILES string: [O-][N+](=O)c1nccn1CC(=O)NCc2ccccc2
• InChI: 1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
• InChI key: CULUWZNBISUWAS-UHFFFAOYSA-N

Descripción

General description

N-Benzyl-2-nitro-1H-imidazole-1-acetamide (Benznidazole) is a nitro-heterocyclic compound. It is widely employed drug for the treatment of Chagas disease. It exhibits three polymorphic forms..

Application

N-Benzyl-2-nitro-1H-imidazole-1-acetamide (Benznidazole) may be used as reference drug for the extraction of guaianolide from the aerial parts of Tanacetum parthenium and to evaluate its in vitro antiprotozoal activity.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves