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Merck

371173

Sigma-Aldrich

Methyl pyruvate

90%, technical grade

Sinónimos:

Pyruvic acid methyl ester

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About This Item

Fórmula lineal:
CH3COCO2CH3
Número de CAS:
Peso molecular:
102.09
Beilstein/REAXYS Number:
1361953
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

Quality Level

assay

90%

form

liquid

refractive index

n20/D 1.404 (lit.)

bp

134-137 °C (lit.)

solubility

ethanol: soluble 1.1 g/10 mL, clear, colorless to almost colorless

density

1.13 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

COC(=O)C(C)=O

InChI

1S/C4H6O3/c1-3(5)4(6)7-2/h1-2H3

InChI key

CWKLZLBVOJRSOM-UHFFFAOYSA-N

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General description

Methyl pyruvate is a pyruvic ester. Surface conditions during Pt/silica EUROPT-1 modified by cinchonidine catalyzed by enantioselective hydrogenation of methyl pyruvate to R-(+)-methyl lactate were investigated. Enantioselective hydrogenation of methyl pyruvate over finely dispersed polyvinylpyrrolidone-stabilized and the corresponding alumina-supported iridium clusters modified with cinchonidine was studied. The molecular orientation and conformation of methyl pyruvate on Ni(111) surface has been investigated in the temperature range 105-220K. Methyl pyruvate is reported to stimulate insulin secretion in vitro and in vivo.

Application

Methyl pyruvate may be used to investigate the adsorption and reactivity of methyl pyruvate on Pt{111}. It may be used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

116.6 °F - closed cup

flash_point_c

47 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Fundamental aspects of enantioselective heterogeneous catalysis: the surface chemistry of methyl pyruvate on Pt {111}.
The Journal of Physical Chemistry B, 104(41), 9696-9703 (2000)
Enantioselective hydrogenation of methyl pyruvate over polymer-stabilized and supported iridium clusters.
Zuo X, et al.
J. Mol. Catal. A: Chem., 147(1), 63-72 (1999)
Bo Fan et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(3), 1003-1011 (2017-10-03)
Tetrandrine and Fangchinoline (Fcn) are two natural products that are found in Stephania tetrandra. Tetrandrine is a known anti-bladder cancer compound, but the effects of Fcn on bladder cancer have been previously unclear. In the present study, we focused on
Emma Heart et al.
American journal of physiology. Endocrinology and metabolism, 292(5), E1295-E1300 (2007-01-11)
Pulsatile insulin output, paralleled by oscillations in intracellular Ca(2+), reflect oscillating metabolism within beta-cells in response to secretory fuels. Here we question whether oscillatory periodicity is conserved or varied from stimulation to stimulation, whether glycolysis is essential for the manifestation
Orientation and conformation of methyl pyruvate on Ni (111).
Castonguay M, et al.
Journal of the American Chemical Society, 122(3), 518-524 (2000)

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