318035

(S)-(−)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid

≥99%

• Sinónimos: (−)-MTPA, Mosher’s acid
• Fórmula lineal: C₆H₅C(OCH₃)(CF₃)CO₂H
• Número de CAS: 17257-71-5
• Peso molecular: 234.17
• Beilstein/REAXYS Number: 4684048
• EC Number: 241-292-1
• MDL number: MFCD00064200
• UNSPSC Code: 12352112
• PubChem Substance ID: 24859111
• NACRES: NA.22

Propiedades

• Quality Level: 200
• assay: ≥99%
• optical activity: [α]18/D −72°, c = 1.6 in methanol
• optical purity: ee: 99% (GLC)
• refractive index: n20/D 1.474 (lit.)
• bp: 95-97 °C/0.05 mmHg (lit.)
• mp: 46-49 °C (lit.)
• density: 1.303 g/mL at 25 °C (lit.)
• functional group: carboxylic acid; ether; fluoro; phenyl
• storage temp.: 2-8°C
• SMILES string: CO[C@](C(O)=O)(c1ccccc1)C(F)(F)F
• InChI: 1S/C10H9F3O3/c1-16-9(8(14)15,10(11,12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,14,15)/t9-/m0/s1
• InChI key: JJYKJUXBWFATTE-VIFPVBQESA-N

Descripción

General description

(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid is commonly used as a derivatizing agent in Mosher ester analysis and Mosher amide analysis, which are NMR-based methods for determining the absolute configuration of the chiral carbon center in secondary alcohols and amines, respectively.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

doi:10.1038/nprot.2007.354

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves