136441

Dimethyl malonate

98%

• Sinónimos: Dimethyl propanedioate, Malonic acid dimethyl ester
• Fórmula lineal: CH₂(COOCH₃)₂
• Número de CAS: 108-59-8
• Peso molecular: 132.11
• Beilstein/REAXYS Number: 774261
• EC Number: 203-597-8
• MDL number: MFCD00008460
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848281
• NACRES: NA.22

Propiedades

• vapor density: >1 (vs air)
• assay: 98%
• form: liquid
• refractive index: n20/D 1.413 (lit.)
• bp: 180-181 °C (lit.)
• mp: −62 °C (lit.)
• solubility: alcohol: miscible; diethyl ether: miscible; oil: miscible; water: slightly soluble
• density: 1.156 g/mL at 25 °C (lit.)
• functional group: ester
• SMILES string: COC(=O)CC(=O)OC
• InChI: 1S/C5H8O4/c1-8-4(6)3-5(7)9-2/h3H2,1-2H3
• InChI key: BEPAFCGSDWSTEL-UHFFFAOYSA-N

Descripción

General description

Dimethyl malonate undergoes enantioselective palladium-catalyzed allylic substitution reaction with 1,3-diphenylprop-2-enyl acetate to yield diastereomeric pure thienylpyridines.

Application

Dimethyl malonate was used in gold catalyzed oxidative esterification of glycerol, 1,2-propanediol and 1,3-propanediol.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 185.0 °F - closed cup
• flash_point_c: 85 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter