D2438

Dimethyl sulfoxide

sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

• Synonym(s): DMSO
• Linear Formula: (CH₃)₂SO
• CAS Number: 67-68-5
• Molecular Weight: 78.13
• Beilstein: 506008
• EC Number: 200-664-3
• MDL number: MFCD00002089
• UNSPSC Code: 12191502
• PubChem Substance ID: 24893688
• NACRES: NA.75

Properties

• grade: BioPerformance Certified
• Quality Level: 400
• Agency: USP XXIV; meets EP testing specifications; meets USP testing specifications
• vapor density: 2.7 (vs air)
• vapor pressure: 0.42 mmHg ( 20 °C)
• sterility: sterile-filtered
• form: liquid
• autoignition temp.: 573 °F
• expl. lim.: 42 %, 63 °F
• technique(s): cell culture | hybridoma: suitable; cryopreservation: suitable
• impurities: ≤0.1% water
• color: colorless
• refractive index: n20/D 1.479 (lit.)
• bp: 189 °C (lit.)
• mp: 16-19 °C (lit.)
• solubility: H₂O: miscible (completely)
• density: 1.10 g/mL (lit.)
• SMILES string: CS(C)=O
• InChI: 1S/C2H6OS/c1-4(2)3/h1-2H3
• InChI key: IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Description

General description

Dimethyl sulfoxide (DMSO) is an aprotic solvent. Therapeutic and toxic molecules that are not soluble in water are often soluble in DMSO. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. DMSO is used to prepare stock solutions of various molecules and is also used as a control for these molecules. It has been used in cell migration assay for dissolving post-migration cells. BPC-tested DMSO also meets the requirements of biotechnology and tissue engineering applications.

Application

Dimethyl sulfoxide has been used as a vehicle control to culture and induce hepatic stellate cells (HSCs) activation in vivo. It has also been used to prepare a stock solution to study the cytotoxicity of ferulic acid (FA) on nucleus pulposus (NP) cells.

Features and Benefits

Ready-to-use sterile filtered product conveniently packaged in septum screw-capped amber bottles. Meets USP and EP testing requirements

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves