Skip to Content
Merck
All Photos(1)

Documents

49752

Sigma-Aldrich

2-Phospho-L-ascorbic acid trisodium salt

≥95.0% (HPLC)

Synonym(s):

L-Ascorbic acid 2-phosphate trisodium salt, Sodium L-ascorbyl-2-phosphate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H6Na3O9P · xH2O
CAS Number:
66170-10-3
Molecular Weight:
322.05 (anhydrous basis)
MDL number:
MFCD03095479
UNSPSC Code:
12352205
NACRES:
NA.79

biological source

synthetic

Quality Level

200

Assay

≥95.0% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤7.5% water (Karl Fischer)

color

white to off-white

pH

9.0-9.5 (25 °C, 30 g/L in H2O)

mp

260 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤10 mg/kg
As: ≤2 mg/kg
Ba: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

InChI

1S/C6H9O9P.3Na/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;/h2,4,7-9H,1H2,(H2,11,12,13);;;/q;3*+1/p-3/t2-,4+;;;/m0.../s1

InChI key

YRWWOAFMPXPHEJ-OFBPEYICSA-K

Application

2-Phospho-L-ascorbic acid trisodium salt has been used as medium supplement in Dulbecco′s Modified Eagle Medium (DMEM) for adipose-derived stem cells, human mesenchymal stem cells and osteoblast cells.

Biochem/physiol Actions

L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays. L-Ascorbic acid 2-phosphate may be used in cell differentiation and tissue engineering applications. Asc-2P is used in studies of gene repression, such as the repression of dihydrotestosterone-induced dickkopf-1 expression.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Regenerative therapy and cancer: in vitro and in vivo studies of the interaction between adipose-derived stem cells and breast cancer cells from clinical isolates
Zimmerlin L, et al.
Tissue Engineering: Part A, 17(1-2), 93-106 (2010)
Xiaojun Ji et al.
Life sciences, 231, 116674-116674 (2019-07-26)
Hypertrophic scar formation is a fibroproliferative disorder caused by abnormal wound healing. At present, there are limited treatment strategies for hypertrophic scars. In this study, we identified an endogenous peptide, LYENRL, through peptidomics screening that is downregulated in scar skin
Martin L Decaris et al.
Annals of biomedical engineering, 39(4), 1174-1185 (2010-12-02)
The presentation of extracellular matrix (ECM) proteins provides an opportunity to instruct the phenotype and behavior of responsive cells. Decellularized cell-secreted matrix coatings (DM) represent a biomimetic culture surface that retains the complexity of the natural ECM. Microenvironmental culture conditions
Kejun Feng et al.
Biosensors & bioelectronics, 26(7), 3187-3191 (2011-01-18)
Here a highly sensitive electrochemical method is described for the detection of point mutation in DNA. Polymerization extension reaction is applied to specifically initiate enzymatic electrochemical amplification to improve the sensitivity and enhance the performance of point mutation detection. In
L Yang et al.
Journal of dental research, 96(2), 186-191 (2016-12-09)
In vitro expanded cell populations can contribute to bioengineered tooth formation but only as cells that respond to tooth-inductive signals. Since the success of whole tooth bioengineering is predicated on the availability of large numbers of cells, in vitro cell
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service