Skip to Content
Merck
All Photos(1)

Key Documents

398276

Sigma-Aldrich

Diisopropyl ether

contains either BHT or hydroquinone as stabilizer, ACS reagent, ≥99.0%

Synonym(s):

Isopropyl ether

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)2CHOCH(CH3)2
CAS Number:
Molecular Weight:
102.17
Beilstein:
1731256
EC Number:
MDL number:
UNSPSC Code:
12191502
PubChem Substance ID:
NACRES:
NA.07
grade:
ACS reagent
bp:
68-69 °C (lit.)
vapor pressure:
120 mmHg ( 20 °C)
Pricing and availability is not currently available.

grade

ACS reagent

Quality Level

vapor density

3.5 (vs air)

vapor pressure

120 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

827 °F

contains

either BHT or hydroquinone as stabilizer

expl. lim.

1-21 %, 100 °F

dilution

(for analytical testing)

impurities

≤0.0007 meq/g Titr. acid
≤0.05% Peroxide (as C6H14O2)

evapn. residue

≤0.01%

color

APHA: ≤25

refractive index

n20/D 1.367 (lit.)

bp

68-69 °C (lit.)

mp

−85 °C (lit.)

density

0.725 g/mL at 25 °C (lit.)

SMILES string

CC(C)OC(C)C

InChI

1S/C6H14O/c1-5(2)7-6(3)4/h5-6H,1-4H3

InChI key

ZAFNJMIOTHYJRJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Diisopropyl ether (DIPE) is branched ether.[1] It is a peroxide forming solvent. This process is catalyzed by heat, light and oxygen. For such solvents small amount of stabilizers like BHT (butylated hydroxytoluene) or hydroquinone is added which removes the free radicals that form peroxides. DIPE has been proposed as a potential alternative oxygenated fuel additive.[1][2] Several methods have been proposed for its synthesis using acetone as starting material.[2][3] The molecular structure and conformation has been studied using gas-phase electron diffusion.[4] Its potential carcinogenicity has been studied in Sprague-Dawley rats.[5]

Application

Diisopropyl ether may be used as a solvent in the following processes:
  • Resolution of secondary alcohols.[6]
  • Enantioselective acylation of 1-phenethylamine.[7]
  • Synthesis of aliphatic and aromatic cyanohydrins.[8]

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-20.2 °F - closed cup

Flash Point(C)

-29 °C - closed cup


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Diisopropyl ether syntheses from crude acetone.
Knifton JF and D PSE.
Catalysis Letters, 57(4), 193-197 (1999)
Resolution of secondary alcohols using lipase in diisopropyl ether.
Bevinakatti HS, et al.
The Journal of Organic Chemistry, 54(10), 2453-2455 (1989)
Diisopropyl ether one-step generation from acetone-rich feedstocks.
Taylor RJ, et al.
Catalysis Letters, 68(1-2), 1-5 (2000)
Molecular structure and conformation of diisopropyl ether: a gas electron diffraction investigation.
Takeuchi H, et al.
The Journal of Physical Chemistry, 91(5), 1015-1019 (1987)
Cross-linked enzyme aggregates (CLEAs): stable and recyclable biocatalysts.
Sheldon RA.
Biochemical Society Transactions, 35(6) (2007)

Protocols

A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service