88580
Phenothiazine
purum, ≥98.0% (GC)
Synonym(s):
PTZ, 10H-Phenothiazine
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All Photos(4)
About This Item
Empirical Formula (Hill Notation):
C12H9NS
CAS Number:
Molecular Weight:
199.27
Beilstein:
143237
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23
Recommended Products
grade
purum
Quality Level
Assay
≥98.0% (GC)
form
pellets
bp
371 °C (lit.)
mp
182-187 °C (lit.)
183-187 °C
SMILES string
N1c2ccccc2Sc3ccccc13
InChI
1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H
InChI key
WJFKNYWRSNBZNX-UHFFFAOYSA-N
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General description
The structure of phenothiazine is rigid, being tricyclic. It is known to alter dopamine (3,4-dihydroxyphenethylamine). Its use as an electron donor is based on its unique hole transporting ability, electron releasing nitrogen and sulfur heteroatoms and its non-planar structure leading to lower molecular aggregation.
Application
Phenothiazine finds uses in metal free organic dye sensitizers, dyes and antioxidants.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2 Oral
Target Organs
Blood
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Asif M, et al
Arabian Journal of Chemistry null
Photodegradation of trimeprazine triggered by self-photogenerated singlet molecular oxygen
Waseem A, et al
Journal of Saudi Chemical Society (2012)
A S Horn et al.
Proceedings of the National Academy of Sciences of the United States of America, 68(10), 2325-2328 (1971-10-01)
Phenothiazines and butyrophenones are known to alter dopamine (3,4-dihydroxyphenethylamine) metabolism in the brain in a fashion suggesting that they may block dopamine receptors. We observed, using Dreiding molecular models, that dopamine in its solid-state conformation is superimposable upon a portion
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease
Carsten K, et al
Proceedings of the National Academy of Sciences of the USA, 98(17), 9834-9841 (2001)
Thankamoniamma Manju et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 11(11), 1744-1755 (2012-09-04)
The reaction pathways following electronic excitation of 10-methyl phenothiazine (MPS) in the presence of oxygen have been investigated as a contribution to establish the mechanisms involved in the phototoxic reactions related to phenothiazine drugs. In the context of previously published
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