539996

Acetic anhydride

99.5%

• Synonym(s): Acetanhydride, Acetic acid anhydride, Acetyl acetate, Acetyl anhydride, Ethanoic anhydride
• Linear Formula: (CH₃CO)₂O
• CAS Number: 108-24-7
• Molecular Weight: 102.09
• Beilstein: 385737
• EC Number: 203-564-8
• MDL number: MFCD00008705
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878429
• NACRES: NA.21

Properties

• vapor density: 3.5 (vs air)
• Quality Level: 200
• vapor pressure: 10 mmHg ( 36 °C); 4 mmHg ( 20 °C)
• Assay: 99.5%
• autoignition temp.: 629 °F
• expl. lim.: 10.3 %
• refractive index: n20/D 1.390 (lit.)
• bp: 138-140 °C (lit.)
• mp: −73 °C (lit.)
• solubility: water: slightly soluble
• density: 1.08 g/mL (lit.)
• SMILES string: CC(=O)OC(C)=O
• InChI: 1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
• InChI key: WFDIJRYMOXRFFG-UHFFFAOYSA-N

Description

General description

Acetic anhydride is a carboxylic acid anhydride commonly used for the acetylation of amines and alcohols. It undergoes exothermic reaction on addition of water to form acetic acid. The photodecomposition of acetic anhydride has been studied over the temperature range from 60-160°C. The impact of treating pine wood with acetic anhydride has been investigated to evaluate the toughness of pine wood.

Application

Acetic anhydride has been used in the preparation of 6-dimethylamino-2,3-naphthalenedicarboxylic anhydride. It has also been used to generate acetate ions during high resolution chemical ionization mass spectrometry (CI-ToFMS) analysis.

Safety Information

• Pictograms: GHS02,GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H226,H302,H314,H330
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 120.2 °F - closed cup
• Flash Point(C): 49 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves