A 2 mM (50 µg/47 µl) solution of KT 5720 (Cat. No. 420320) in DMSO.
Reconstitution
Following the initial thaw, aliquot and freeze (20°C).
Other Notes
Simpson, C.S., and Morris, B.J. 1995. Neurosci.68, 97. Cabell, L, and Audesirk, G. 1993. Int. J. Dev. Neurosci.11, 357. Gadbois, D.M., et al. 1992. Proc. Natl. Acad. Sci. USA89, 8626. Kase, H., et al. 1987. Biochem. Biophys. Res. Commun.142, 436.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
188.6 °F - (refers to pure substance)
Flash Point(C)
87 °C - (refers to pure substance)
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Neuronal activity induces topoisomerase IIβ (Top2B) to generate DNA double-strand breaks (DSBs) within the promoters of neuronal early response genes (ERGs) and facilitate their transcription, and yet, the mechanisms that control Top2B-mediated DSB formation are unknown. Here, we report that
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